从内生真菌特异青霉LGT-4中分离出两种新化合物，去乙酰异麦芽菌素A和B。
Two new compounds, deacetylisowortmins A and B, isolated from an endophytic Fungus, Talaromyces wortmannii LGT-4.
作者信息
Fu Guang-Chao, Yang Zhong-Duo, Zhou Shuang-Yan, Yu Hai-Tao, Zhang Fei, Yao Xiao-Jun
机构信息
a School of Life Science and Engineering , Lanzhou University of Technology , Lanzhou , P.R. China.
b The Provincial Education Key Laboratory of Screening, Evaluation and Advanced Processing of Traditional Chinese Medicine and Tibetan Medicine, School of Life Science and Engineering , Lanzhou University of Technology , Lanzhou , P.R. China.
出版信息
Nat Prod Res. 2016 Jul;30(14):1623-7. doi: 10.1080/14786419.2015.1129329. Epub 2016 Jan 4.
Two new compounds, deacetylisowortmins A (1) and B (2), were isolated from Talaromyces wortmannii LGT-4. Their structures were established by 1D and 2D NMR spectra, as well as comparison of the experimental and calculated electronic circular dichroism spectra. Monoamine oxidase and acetylcholinesterase inhibitory activities of 1 and 2 were also evaluated.
从特异青霉LGT-4中分离出两种新化合物，去乙酰异麦芽霉素A（1）和B（2）。通过一维和二维核磁共振光谱以及实验和计算的电子圆二色光谱的比较确定了它们的结构。还评估了1和2的单胺氧化酶和乙酰胆碱酯酶抑制活性。
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