Leyendecker B, Klapp B F, Scheer J W, Bartholomew U
Abteilung für Psychosomatische Medizin und Psychotherapie, Universitätsklinikum Rudolf Virchow, Berlin.
Z Gastroenterol. 1989 Oct;27(10):619-23.
As part of a study on the relationship between psychosocial factors and the course of acute viral hepatitis A, B and NANB, bodily complaints of 41 patients were examined and two major complaint factors evolved. One complex of specific liver complaints, consisting of fatigue and an excessive need for sleep, gastrointestinal and skin symptoms, correlated with the degree of liver damage and can most readily be regarded as organdependent. A smaller group of general complaints did not correlate with liver damage. It seems to represent a complex symptomatology, which is probably partly psychologically determined. Patients with hepatitis B suffer the severest liver damage and present the most specific complaints. Patients with hepatitis NANB show the mildest symptomatology and patients with hepatitis A hold a medium position. The hepatitis types do not differ in respect to their general complaints. While sex-related differences in the level of complaints are still visible during the prodromal phase, sex and age-related differences disappear during the acute phase. Further morbidity also does not influence symptomatology at this stage. At discharge, however, sex-related differences and the effects of further morbidity on the remaining complaints reaper.
作为一项关于心理社会因素与急性甲型、乙型和非甲非乙型病毒性肝炎病程之间关系研究的一部分，对41例患者的身体不适症状进行了检查，并确定了两个主要的不适因素。一组由疲劳、过度嗜睡、胃肠道和皮肤症状组成的特定肝脏不适症状，与肝脏损害程度相关，最容易被视为器官依赖性症状。另一组较少的一般不适症状与肝脏损害无关。它似乎代表了一种复杂的症状学，可能部分由心理因素决定。乙型肝炎患者肝脏损害最严重，表现出最具特异性的不适症状。非甲非乙型肝炎患者症状最轻，甲型肝炎患者处于中间位置。各型肝炎在一般不适症状方面没有差异。在前驱期仍可见到与性别相关的不适程度差异，但在急性期，与性别和年龄相关的差异消失。在此阶段，进一步发病也不影响症状表现。然而，在出院时，与性别相关的差异以及进一步发病对剩余不适症状的影响又显现出来。
