Jezek P, Chalupa P, Kolácný I, Horák Z
Klinika infekcních chorob Masarykovy universzity, Brno.
Vnitr Lek. 1990 Dec;36(12):1151-7.
Comparison of large groups of patients with acute viral hepatitis A (HA), B (HB) and non-A, non-B (HNANB) revealed that the highest percentage of anicteric forms is found in HA (44.8%) followed by HNANB (27.3%) and the lowest percentage in HB (23.6%). Investigation of mean values of biochemical functional liver tests showed that 1. the highest mean values of bilirubinaemia, ALT and AST were recorded in HB. The differences are statistically significantly higher (p less than 0.01) than in the two remaining types. 2. The difference between the cholesterol serum level, GMT and ALP in HB and HNANB on the one hand and HA on the other hand was at the same level of significance. 3. The transaminase activity is only slightly higher in HA than in HNANB, the differences are not significant (p greater than 0.05). 4. The cholestatic features are more marked in HNANB than in HA. The differences are also significant (p less than 0.01). In the clinical picture in acute HNANB symptoms of influenza predominated (53.33%), followed by digestive complaints (47.5%) and the percentage of articular complaints was lowest (24.17%). Analysis of 24 cases of fulminant forms of viral hepatitis revealed that this course was most frequent in HB (50%), followed by HNANB (41.7%) and least frequent in HA (8.3%).
对大量急性甲型肝炎（HA）、乙型肝炎（HB）和非甲非乙型肝炎（HNANB）患者进行比较后发现，无黄疸型在HA中所占比例最高（44.8%），其次是HNANB（27.3%），在HB中所占比例最低（23.6%）。对肝脏生化功能检查平均值的研究表明：1. 胆红素血症、谷丙转氨酶（ALT）和谷草转氨酶（AST）的平均最高值出现在HB中。这些差异在统计学上显著高于其余两种类型（p小于0.01）。2. HB和HNANB与HA相比，血清胆固醇水平、γ-谷氨酰转肽酶（GMT）和碱性磷酸酶（ALP）的差异具有相同的显著水平。3. HA中的转氨酶活性仅略高于HNANB，差异不显著（p大于0.05）。4. HNANB中的胆汁淤积特征比HA更明显。差异也具有显著性（p小于0.01）。在急性HNANB的临床表现中，流感样症状占主导（53.33%），其次是消化系统症状（47.5%），关节症状的比例最低（24.17%）。对24例暴发性病毒性肝炎病例的分析显示，这种病程在HB中最为常见（50%），其次是HNANB（41.7%），在HA中最不常见（8.3%）。
