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Performance evaluation of Warshall algorithm and dynamic programming for Markov chain in local sequence alignment.

作者信息

Khan Mohammad Ibrahim, Kamal Md Sarwar

机构信息

Department of Computer Science & Engineering., Chittagong University of Engineering and Technology, Chittagong, 4349, Bangladesh.

出版信息

Interdiscip Sci. 2015 Mar;7(1):78-81. doi: 10.1007/s12539-013-0042-7. Epub 2014 Aug 9.

DOI:10.1007/s12539-013-0042-7
PMID:25118652
Abstract

Markov Chain is very effective in prediction basically in long data set. In DNA sequencing it is always very important to find the existence of certain nucleotides based on the previous history of the data set. We imposed the Chapman Kolmogorov equation to accomplish the task of Markov Chain. Chapman Kolmogorov equation is the key to help the address the proper places of the DNA chain and this is very powerful tools in mathematics as well as in any other prediction based research. It incorporates the score of DNA sequences calculated by various techniques. Our research utilize the fundamentals of Warshall Algorithm (WA) and Dynamic Programming (DP) to measures the score of DNA segments. The outcomes of the experiment are that Warshall Algorithm is good for small DNA sequences on the other hand Dynamic Programming are good for long DNA sequences. On the top of above findings, it is very important to measure the risk factors of local sequencing during the matching of local sequence alignments whatever the length.

摘要

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