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阵发性夜间血红蛋白尿患者壁内血肿后延迟性十二指肠梗阻:一例报告

Delayed duodenal obstruction after intramural hematoma in a patient with paroxysmal nocturnal hemoglobinuria: A case report.

作者信息

Tezcaner Tugan, Ekici Yahya, Kırnap Mahir, Kural Feride, Moray Gökhan

机构信息

Department of General Surgery, Başkent University School of Medicine, Ankara Hospital, Turkey.

Department of General Surgery, Başkent University School of Medicine, Ankara Hospital, Turkey.

出版信息

Int J Surg Case Rep. 2014;5(9):605-7. doi: 10.1016/j.ijscr.2014.06.022. Epub 2014 Jul 24.

Abstract

INTRODUCTION

Paroxysmal nocturnal hemoglobinuria (PNH) is a clonal stem cell disorder of hematopoietic cells. Gastrointestinal complications of PNH are rare and mostly related with intravascular thrombosis or intramural hematoma.

PRESENTATION OF CASE

We describe a case of a man with PNH complicated by intramural duodenal hematoma initially treated with supportive care. Three months after his first admission; he was admitted to the emergency department with abdominal pain, nausea and vomiting. He had undergone to surgery because of duodenal obstruction was treated with duodenojejunal by-pass surgery.

DISCUSSION

Patients were healed from gastrointestinal complications could suffer from gastrointestinal strictures, which cause wide spread symptoms ranging from chronic abdominal pain and anorexia to intestinal obstruction.

CONCLUSION

We report a rare intestinal obstruction case caused by stricture at the level of ligamentum Treitz with PNH. The possibility simply has to be borne in mind that strictures can be occurring at hematoma, ischemia or inflammation site of gastrointestinal tract.

摘要

引言

阵发性睡眠性血红蛋白尿(PNH)是一种造血细胞的克隆性干细胞疾病。PNH的胃肠道并发症罕见,主要与血管内血栓形成或壁内血肿有关。

病例介绍

我们描述了一例PNH并发十二指肠壁内血肿的男性病例,最初采用支持治疗。首次入院三个月后,他因腹痛、恶心和呕吐被收入急诊科。由于十二指肠梗阻,他接受了手术,采用十二指肠空肠旁路手术进行治疗。

讨论

胃肠道并发症治愈的患者可能会出现胃肠道狭窄,这会导致从慢性腹痛、厌食到肠梗阻等广泛症状。

结论

我们报告了一例罕见的由Treitz韧带水平狭窄引起的肠梗阻病例,该患者患有PNH。必须牢记,胃肠道血肿、缺血或炎症部位可能会出现狭窄。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4f3a/4201022/7abae1443f72/gr1.jpg

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