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匹配的英国和德国患者队列中初次全髋关节置换术后术前与术后健康相关生活质量及住院时间的比较。

Comparison of pre- and post-operative health-related quality of life and length of stay after primary total hip replacement in matched English and German patient cohorts.

作者信息

Vogl Matthias, Leidl Reiner, Plötz Werner, Gutacker Nils

机构信息

Institute of Health Economics and Health Care Management (IGM), Helmholtz Zentrum München, German Research Center for Environmental Health, P.O. Box 1129, 85758, Neuherberg, Munich, Germany,

出版信息

Qual Life Res. 2015 Feb;24(2):513-20. doi: 10.1007/s11136-014-0782-9. Epub 2014 Aug 15.

DOI:10.1007/s11136-014-0782-9
PMID:25124253
Abstract

PURPOSE

We compare pre- and post-operative health-related quality of life (HRQoL) and length of stay after total hip replacement (THR) in matched German and English patient cohorts to test for differences in admission thresholds, clinical effectiveness and resource utilisation between the healthcare systems.

METHODS

German data (n = 271) were collected in a large orthopaedic hospital in Munich, Germany; English data (n = 26,254) were collected as part of the national patient-reported outcome measures programme. HRQoL was measured using the EuroQoL-5D instrument. Propensity score matching was used to construct two patient cohorts that are comparable in terms of preoperative patient characteristics.

RESULTS

Before matching, patients in England showed lower preoperative EQ-5D scores (0.35 vs 0.52, p < 0.001) and experienced a larger improvement in HRQoL (0.43 vs 0.33, p < 0.001) than German patients. Patients in the German cohort were more likely to report no or only moderate problems with mobility and pain preoperatively than their English counterparts. After matching, improvements in HRQoL were comparable (0.32 vs 0.33, p = 0.638); post-operative scores were slightly higher in the German cohort (0.82 vs 0.85, p = 0.585). Length of stay was substantially lower in England than in Germany (4.5 vs 9.0 days, p < 0.001).

CONCLUSIONS

Our results highlight differences in preoperative health status between countries, which may arise due to different admission thresholds and access to surgery. In terms of quality of life, THR surgery is equally effective in both countries when performed on similar patients, but hospital stay is shorter in England.

摘要

目的

我们比较德国和英国匹配患者队列在全髋关节置换术(THR)前后的健康相关生活质量(HRQoL)和住院时间,以检验医疗系统在入院门槛、临床疗效和资源利用方面的差异。

方法

德国的数据(n = 271)收集于德国慕尼黑一家大型骨科医院;英国的数据(n = 26,254)作为国家患者报告结局测量计划的一部分进行收集。使用欧洲五维健康量表(EuroQoL-5D)测量HRQoL。倾向得分匹配用于构建两个在术前患者特征方面具有可比性的患者队列。

结果

匹配前,英国患者术前的EQ-5D评分较低(0.35对0.52,p < 0.001),且HRQoL的改善幅度大于德国患者(0.43对0.33,p < 0.001)。与英国同行相比,德国队列中的患者术前更有可能报告无或仅有中度的行动和疼痛问题。匹配后,HRQoL的改善相当(0.32对0.33,p = 0.638);德国队列的术后评分略高(0.82对0.85,p = 0.585)。英国的住院时间显著低于德国(4.5天对9.0天,p < 0.001)。

结论

我们的结果凸显了各国术前健康状况的差异,这可能是由于不同的入院门槛和手术可及性导致的。在生活质量方面,当对相似患者进行THR手术时,两国的手术效果相当,但英国的住院时间更短。

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