Biswas Mohitosh, Roy Manobendro Nath, Manik Md Imran Nur, Hossain Md Shahid, Tapu S M Tafsirul Alam, Moniruzzaman Md, Sultana Sharmin
Department of Pharmacy, University of Rajshahi, Rajshahi, Bangladesh.
BMC Public Health. 2014 Aug 14;14:847. doi: 10.1186/1471-2458-14-847.
Antibiotic self medication is highly prevalent in the developing countries due to easy availability and poor regulatory controls for selling these drugs. The purpose of this study was to evaluate the prevalence of self-medication with antibiotics for the treatment of various diseases by the peoples of Rajshahi city in Bangladesh.
A cross-sectional survey was conducted to the patient's (n = 1300) at eight locations of Rajshahi city in Bangladesh from March to April, 2014. The locations were selected by convenience and the study population within each study area was randomly selected. The survey was self-administered and included questions pertaining to self medicated drugs and antibiotic usage patterns as well. Data were analyzed using descriptive statistics.
It was found that 347 (26.69%) out of 1300 participants experienced self medication with antibiotics. Over fifty percent of the patients studied were between the ages of 21-30 years with 83.57% of them being males and 16.43% females. The highest percentage of self medicated antibiotics was metronidazole (50.43%) followed by azithromycin (20.75%), ciprofloxacin (11.53%), amoxicillin (10.37%) and tetracycline (7.49%) respectively. The key reasons for the self medication of antibiotics was the pre-experience (45.82%), suggestions from others (28.24%) and knowledgeable of the antibiotics (16.14%). The perceived symptoms to purchase the antibiotics independently was dysentery, diarrhea and food poisoning (36.02%), cold, cough and fever (28.24%), infection (12.97%), dental carries and toothache (9.22%), irritable bowel syndrome (3.46%), acne (4.32%), ear and throat pain (2.31%). The duration of maximum antibiotics usage was ranges between 0-10 years. Only 4.32% patient's used self medicated antibiotics longer than 10 years. The patient's compliance for self medication of antibiotics varies from excellent to no comments whereas only 6.92% patients reported side effects for the self medication of antibiotics.
The results of this study confirm that antibiotic self-medication is a relatively frequent problem in Bangladesh. Drug Administration of Bangladesh should implement the regulatory controls immediately on the distribution and selling of antibiotics in order to reduce the frequency of antibiotic misuse.
由于抗生素易于获取且销售监管不力,在发展中国家自我药疗现象极为普遍。本研究旨在评估孟加拉国拉杰沙希市居民使用抗生素自我药疗治疗各种疾病的流行情况。
2014年3月至4月,在孟加拉国拉杰沙希市的8个地点对1300名患者进行了横断面调查。这些地点是方便选取的,每个研究区域内的研究人群是随机选取的。该调查采用自填式问卷,其中包括有关自我药疗药物和抗生素使用模式的问题。数据采用描述性统计进行分析。
在1300名参与者中,有347人(26.69%)曾使用抗生素进行自我药疗。研究的患者中超过50%年龄在21至30岁之间,其中83.57%为男性,16.43%为女性。自我药疗使用最多的抗生素是甲硝唑(50.43%),其次分别是阿奇霉素(20.75%)、环丙沙星(11.53%)、阿莫西林(10.37%)和四环素(7.49%)。抗生素自我药疗的主要原因是既往经验(45.82%)、他人建议(28.24%)和对抗生素的了解(16.14%)。自行购买抗生素的常见症状是痢疾、腹泻和食物中毒(36.02%)、感冒、咳嗽和发烧(28.24%)、感染(12.97%)、龋齿和牙痛(9.22%)、肠易激综合征(3.46%)、痤疮(4.32%)、耳痛和咽痛(2.31%)。抗生素使用时间最长的范围在0至10年之间。只有4.32%的患者使用自我药疗抗生素超过10年。患者对抗生素自我药疗的依从性从极好到未作评价不等,而只有6.92%的患者报告了抗生素自我药疗的副作用。
本研究结果证实,在孟加拉国抗生素自我药疗是一个较为常见的问题。孟加拉国药品管理部门应立即对抗生素的分销和销售实施监管控制,以减少抗生素滥用的频率。