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卡拉奇非医学专业大学生自我使用抗生素情况的横断面研究

Self-medication with antibiotics among non-medical university students of Karachi: a cross-sectional study.

作者信息

Shah Syed Jawad, Ahmad Hamna, Rehan Rija Binte, Najeeb Sidra, Mumtaz Mirrah, Jilani Muhammad Hashim, Rabbani Muhammad Sharoz, Alam Muhammad Zakariya, Farooq Saba, Kadir M Masood

机构信息

Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan.

出版信息

BMC Pharmacol Toxicol. 2014 Dec 23;15:74. doi: 10.1186/2050-6511-15-74.

Abstract

BACKGROUND

The prevalence of self -medication with antibiotics is quite high in developing countries as opposed to developed countries. Antibiotics are often taken erroneously for certain ailments, without having the appropriate knowledge of their use. This carries potential risks for the individual as well as the community, in form of several side effects such as antibiotic resistance. Therefore the prevalence of self-medicated antibiotics in developing countries needs to be studied.

METHODS

A descriptive cross-sectional study was carried out at six different non-medical universities of Karachi. 431 students were included in the study. Data was collected using self-administered questionnaires and analyzed using SPSS version 19.

RESULTS

50.1% students reported having self-medicated themselves in the past 6 months and 205 (47.6%) reported self-medication with antibiotics. Amoxicillin was the most self-prescribed antibiotic (41.4%). Awareness of the adverse effects of antibiotics was demonstrated by 77.3% of the students and sleep disturbance was the most commonly known (46.5%) side effect. 63.1% denied having any knowledge about antibiotic resistance and only 19.9% correctly knew that indiscriminate use of antibiotics can lead to increased antibiotic resistance.

CONCLUSION

The prevalence of self-medication with antibiotics among the non-medical university students was high despite the awareness of adverse effects. Antibiotic resistance was a relatively unknown terminology.

摘要

背景

与发达国家相比,发展中国家抗生素自我药疗的发生率相当高。人们常常在对某些疾病没有正确用药知识的情况下错误地服用抗生素。这会给个人和社区带来潜在风险,表现为抗生素耐药性等多种副作用。因此,需要对发展中国家抗生素自我药疗的发生率进行研究。

方法

在卡拉奇的六所不同的非医科大学开展了一项描述性横断面研究。431名学生纳入研究。通过自行填写问卷收集数据,并使用SPSS 19版进行分析。

结果

50.1%的学生报告在过去6个月内有过自我药疗行为,205名(47.6%)报告使用过抗生素进行自我药疗。阿莫西林是最常自行开具的抗生素(41.4%)。77.3%的学生知晓抗生素的不良反应,睡眠障碍是最常听说的(46.5%)副作用。63.1%的学生否认了解抗生素耐药性,只有19.9%的学生正确知道滥用抗生素会导致抗生素耐药性增加。

结论

尽管知晓不良反应,但非医科大学生中抗生素自我药疗的发生率仍很高。抗生素耐药性是一个相对陌生的术语。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/585a/4320599/5549c0b99286/40360_2014_362_Fig1_HTML.jpg

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