Saleh Anas, Guirguis Albair, Klika Alison K, Johnson Lucileia, Higuera Carlos A, Barsoum Wael K
Department of Orthopaedic Surgery, Cleveland Clinic, Cleveland, Ohio.
Department of Infectious Disease, Cleveland Clinic, Cleveland, Ohio.
J Arthroplasty. 2014 Nov;29(11):2181-6. doi: 10.1016/j.arth.2014.07.010. Epub 2014 Jul 16.
Unexpected positive intraoperative cultures (UPIC) in presumed aseptic revision arthroplasty can be difficult to interpret. The purpose of this retrospective study was to compare the incidence of subsequent periprosthetic joint infection (PJI) in patients who received antibiotic therapy according to an institutional protocol with those who did not and whether they meet Musculoskeletal Infection Society (MSIS) criteria for PJI. In patients who were treated with antibiotic according to institutional criteria, the incidence of PJI after revision was higher in those who did not meet MSIS criteria (22%) than in those that met MSIS criteria (14%; P > 0.71). UPIC in aseptic revision arthroplasty are not uncommon. PJI cannot be excluded in patients that do not meet MSIS definition.
在假定为无菌性的翻修关节成形术中，意外的术中培养阳性结果（UPIC）可能难以解读。这项回顾性研究的目的是比较按照机构方案接受抗生素治疗的患者与未接受抗生素治疗的患者随后发生假体周围关节感染（PJI）的发生率，以及他们是否符合肌肉骨骼感染学会（MSIS）的PJI标准。在根据机构标准接受抗生素治疗的患者中，不符合MSIS标准的患者翻修后PJI的发生率（22%）高于符合MSIS标准的患者（14%；P>0.71）。无菌性翻修关节成形术中的UPIC并不罕见。不符合MSIS定义的患者不能排除PJI。
