一例以甲胎蛋白水平升高为表现的腹膜后肝外肝细胞癌病例报告。
A case report of retroperitoneal extrahepatic hepatocellular carcinoma presented with elevated level of Alpha fetoprotein.
作者信息
Yuce S, Sahin Oz, Bedir R, Ayaz T, Durakoglugil T
机构信息
Department of Internal Medicine, Recep Tayyip Erdogan University Training and Research Hospital, Rize, Turkey.
Department of Nephrology, Recep Tayyip Erdogan University Training and Research Hospital, Rize, Turkey.
出版信息
Hippokratia. 2014 Jan;18(1):80-2.
Abstract
BACKGROUND
High level of alpha-fetoprotein is usually associated with testis cancer or hepatocellular carcinoma a primary tumor of the liver.
CASE
We report the case of a 72-year-old male patient with chronic renal failure who presented with a high alpha-fetoprotein (AFP) level and a retroperitoneal mass, which was subsequently diagnosed to be an extrahepatic hepatocellular carcinoma.
CONCLUSION
A retroperitoneal mass with elevated AFP level and no detected liver lesions is not always caused by a testicular cancer.
摘要
背景
甲胎蛋白水平升高通常与睾丸癌或肝细胞癌（肝脏的原发性肿瘤）相关。
病例
我们报告一例72岁男性慢性肾衰竭患者，其甲胎蛋白（AFP）水平升高且伴有腹膜后肿块，随后被诊断为肝外肝细胞癌。
结论
AFP水平升高且未检测到肝脏病变的腹膜后肿块并非总是由睾丸癌引起。
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本文引用的文献
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World J Surg Oncol. 2011 May 9;9:47. doi: 10.1186/1477-7819-9-47.
2
American Society of Clinical Oncology Clinical Practice Guideline on uses of serum tumor markers in adult males with germ cell tumors.美国临床肿瘤学会临床实践指南：男性生殖细胞肿瘤患者血清肿瘤标志物的应用
J Clin Oncol. 2010 Jul 10;28(20):3388-404. doi: 10.1200/JCO.2009.26.4481. Epub 2010 Jun 7.
3
Ectopic hepatocellular carcinoma arising from pancreas: a case report and review of the literature.起源于胰腺的异位肝细胞癌：一例报告并文献复习
World J Gastroenterol. 2007 Aug 21;13(31):4270-3. doi: 10.3748/wjg.v13.i31.4270.
4
The progressive elevation of alpha fetoprotein for the diagnosis of hepatocellular carcinoma in patients with liver cirrhosis.肝硬化患者中用于诊断肝细胞癌的甲胎蛋白水平进行性升高。
BMC Cancer. 2007 Feb 8;7:28. doi: 10.1186/1471-2407-7-28.
5
Resection of liver metastases from an alpha-fetoprotein-producing gastric cancer.切除来自产生甲胎蛋白的胃癌的肝转移瘤。
J Nippon Med Sch. 2005 Feb;72(1):66-70. doi: 10.1272/jnms.72.66.
6
Ectopic liver and hepatocarcinogenesis.异位肝脏与肝癌发生
Eur J Gastroenterol Hepatol. 2004 Aug;16(8):727-9. doi: 10.1097/01.meg.0000131037.92864.df.
7
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Acta Chir Belg. 2002 Jun;102(3):210-1. doi: 10.1080/00015458.2002.11679298.
8
The role of serum alpha-fetoprotein estimation in the diagnosis and management of hepatocellular carcinoma.
Clin Liver Dis. 2001 Feb;5(1):145-59. doi: 10.1016/s1089-3261(05)70158-6.
9
Propensity of ectopic liver to hepatocarcinogenesis: case reports and a review of the literature.异位肝发生肝癌的倾向：病例报告及文献综述
Hepatology. 1999 Jan;29(1):57-61. doi: 10.1002/hep.510290144.
10
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Hepatology. 1998 Jan;27(1):273-8. doi: 10.1002/hep.510270140.
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