Liou Kevin, Wolfers Darren, Turner Robert, Bennett Michael, Allan Roger, Jepson Nigel, Cranney Greg
Eastern Heart Clinic, Prince of Wales Hospital, Barker Street, Randwick, 2031, Australia.
Australian Diving and Hyperbaric Medicine Research Group, Prince of Wales Hospital, Barker Street, Randwick, 2031, Australia.
Heart Lung Circ. 2015 Jan;24(1):26-31. doi: 10.1016/j.hlc.2014.07.057. Epub 2014 Jul 17.
Few have examined the influence of patent foramen ovale (PFO) on the phenotype of decompression illness (DCI) in affected divers.
A retrospective review of our database was performed for 75 SCUBA divers over a 10-year period.
Overall 4,945 bubble studies were performed at our institution during the study period. Divers with DCI were more likely to have positive bubble studies than other indications (p<0.001). Major DCI was observed significantly more commonly in divers with PFO than those without (18/1,000 v.s. 3/1,000, p=0.02). Divers affected by DCI were also more likely to require a longer course of hyperbaric oxygen therapy (HBOT) if PFO was present (p=0.038). If the patient experienced one or more major DCI symptoms, the odds ratio of PFO being present on a transoesophageal echocardiogram was 3.2 (p=0.02) compared to those who reported no major DCI symptoms.
PFO is highly prevalent in selected SCUBA divers with DCI, and is associated with a more severe DCI phenotype and longer duration of HBOT. Patients with unexpected DCI with one or more major DCI symptoms should be offered PFO screening if they choose to continue diving, as it may have considerable prognostic and therapeutic implications.
很少有人研究卵圆孔未闭(PFO)对受影响潜水员减压病(DCI)表型的影响。
对我们数据库中75名水肺潜水员进行了为期10年的回顾性研究。
在研究期间,我们机构共进行了4945次气泡研究。患有DCI的潜水员比其他适应症的潜水员更有可能出现阳性气泡研究结果(p<0.001)。与没有PFO的潜水员相比,有PFO的潜水员中观察到的重度DCI明显更常见(18/1000对3/1000,p=0.02)。如果存在PFO,受DCI影响的潜水员也更有可能需要更长疗程的高压氧治疗(HBOT)(p=0.038)。如果患者经历了一种或多种重度DCI症状,与没有重度DCI症状的患者相比,经食管超声心动图显示存在PFO的比值比为3.2(p=0.02)。
PFO在患有DCI的特定水肺潜水员中高度普遍,并且与更严重的DCI表型和更长的HBOT疗程相关。如果选择继续潜水,有意外DCI且有一个或多个重度DCI症状的患者应进行PFO筛查,因为这可能具有重要的预后和治疗意义。