Department of Dermatology, Hôpital Tarnier Cochin, 89 rue d'Assas, 75006 Paris, France.
Department of Dermatology, Hôpital Tarnier Cochin, 89 rue d'Assas, 75006 Paris, France.
Best Pract Res Clin Obstet Gynaecol. 2014 Oct;28(7):946-58. doi: 10.1016/j.bpobgyn.2014.07.005. Epub 2014 Jul 18.
Vulvar dermatoses are inflammatory conditions responsible for chronic or recurrent itching and soreness. The lesions are either circumscribed to the vulva or associated with extragenital localizations which may help to assess the diagnosis. They should be differentiated from infectious or neoplastic diseases which may have clinical similarities. As opposed to the majority of all dermatoses that have a benign and regular course, lichen sclerosus or lichen planus could exceptionally foster the occurrence of an epithelial cancer precursor which may evolve to squamous cell carcinoma. Topical corticosteroids are the mainstay treatment of vulvar dermatosis. We do not know if the treatment of vulvar lichen sclerosus and vulvar lichen planus prevents squamous cell carcinoma.
外阴皮肤病是引起慢性或复发性瘙痒和疼痛的炎症性疾病。病变局限于外阴或与外阴外局部定位相关,这有助于评估诊断。它们应与可能具有临床相似性的感染性或肿瘤性疾病区分开来。与大多数具有良性和常规病程的皮肤病不同,硬化性苔藓或扁平苔藓可能会异常促进上皮癌前体的发生,后者可能进展为鳞状细胞癌。局部皮质类固醇是外阴皮肤病的主要治疗方法。我们不知道治疗外阴硬化性苔藓和外阴扁平苔藓是否可以预防鳞状细胞癌。