Oh Jong Jin, Byun Seoksoo, Hong Sung Kyu, Jeong Chang Wook, Lee Sang Eun
Department of Urology, Seoul National University Bundang Hospital, Seongnam, Korea.
Can Urol Assoc J. 2014 Jul;8(7-8):E471-5. doi: 10.5489/cuaj.1679.
We present comparative outcomes among matched patients who underwent robotic partial nephrectomy (RPN) or open partial nephrectomy (OPN) by a single surgeon at a single institution.
We reviewed the medical records of 200 patients who underwent RPN (n = 100) or OPN (n = 100) between May 2003 and May 2013. The patients who underwent RPN were matched for age, gender, body mass index (BMI), American Society of Anesthesiologists (ASA) score, as well as tumour size, side and location. Perioperative outcomes were compared.
There was no significant difference between the 2 cohorts with respect to patient age, BMI, ASA score, preoperative glomerular filtration rate, tumour size and the R.E.N.A.L. nephrometry score. The mean operative time was longer in the RPN group, but there were no significant differences with respect to warm ischemic time and postoperative renal function. The length of hospitalization and use of postoperative analgesics (ketoprofen) were more favourable in the RPN cohort. There was no significant difference in the mean estimated blood loss, transfusion rate, or complications between the cohorts.
Considering the perioperative and postoperative parameters, RPN is a viable option as a nephron-sparing surgical procedure for small renal masses that yields outcomes comparable to those achieved with OPN. Despite matched cohort analysis among patients who underwent PN by a single surgeon, there may be inherent selection bias; therefore future prospective trials are needed.
我们展示了在单一机构由同一位外科医生进行机器人辅助部分肾切除术(RPN)或开放性部分肾切除术(OPN)的匹配患者中的比较结果。
我们回顾了2003年5月至2013年5月期间接受RPN(n = 100)或OPN(n = 100)的200例患者的病历。接受RPN的患者在年龄、性别、体重指数(BMI)、美国麻醉医师协会(ASA)评分以及肿瘤大小、侧别和位置方面进行了匹配。比较围手术期结果。
两组在患者年龄、BMI、ASA评分、术前肾小球滤过率、肿瘤大小和R.E.N.A.L.肾计量评分方面无显著差异。RPN组的平均手术时间较长,但在热缺血时间和术后肾功能方面无显著差异。RPN队列的住院时间和术后镇痛药(酮洛芬)的使用情况更有利。两组之间的平均估计失血量、输血率或并发症无显著差异。
考虑到围手术期和术后参数,RPN作为一种保留肾单位的手术方法,对于小肾肿块是一种可行的选择,其结果与OPN相当。尽管对由同一位外科医生进行PN的患者进行了匹配队列分析,但可能存在内在的选择偏倚;因此,未来需要进行前瞻性试验。