6至18岁人群的角膜阻力因子和角膜滞后现象

Corneal resistance factor and corneal hysteresis in a 6- to 18-year-old population.

作者信息

Hashemi Hassan, Jafarzadehpur Ebrahim, Mehravaran Shiva, Yekta Abbasali, Ostadimoghaddam Hadi, Norouzirad Reza, Khabazkhoob Mehdi

机构信息

From the Noor Ophthalmology Research Center (Hashemi, Jafarzadehpur, Mehravaran), Noor Eye Hospital, and the Department of Optometry (Jafarzadehpur), Iran University of Medical Sciences, the Department of Epidemiology (Khabazkhoob) Faculty of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, the Refractive Errors Research Center (Yekta, Ostadimoghaddam) and the Department of Optometry (Yekta, Ostadimoghaddam), School of Paramedical Sciences, Mashhad University of Medical Sciences, Mashhad, and the Dezful University of Medical Sciences (Norouzirad), Dezful, Iran.

出版信息

J Cataract Refract Surg. 2014 Sep;40(9):1446-53. doi: 10.1016/j.jcrs.2013.12.019.

DOI:10.1016/j.jcrs.2013.12.019

PMID:25135536

Abstract

PURPOSE

To determine the distribution and normal range of the corneal resistance factor (CRF) and corneal hysteresis (CH) in the 6- to 18-year age range and their relationship with biometric components.

SETTING

Dezful, Iran.

DESIGN

Cross-sectional study.

METHODS

This study of Dezful school children used a multistage, stratified, cluster approach sampling. All students had examinations for biometry, noncycloplegic refraction, and corneal biomechanical properties; the examinations were performed in the same order in all cases.

RESULTS

Of the 864 selected students, 683 participated in the study. The mean CRF and CH was 11.74 mm Hg±1.77 (SD) (95% confidence interval [CI], 11.58-11.89) and 11.49±1.91 mm Hg (95% CI, 11.33-11.65), respectively. In a linear multiple regression model, the CRF significantly correlated with female sex (β coefficient=0.488, P=.013), central corneal thickness (CCT) (β coefficient=.034, P=.001), and keratometry (β-coefficient=0.157, P=.003) and CH significantly correlated with CCT (β coefficient=0.025, P<.001), axial length (β coefficient=-0.303, P=.011), and keratometry (β coefficient=0.11, P=.043). Each year increase in age was associated with a 42-unit decrease in the peak 1 area (P=.003).

CONCLUSIONS

The distribution of CRF and CH in an Iranian population was symmetrical and bell shaped. However, the CRF did not have a normal distribution. The mean CRF and CH were higher than those reported in almost all previous studies.

FINANCIAL DISCLOSURE

No author has a financial or proprietary interest in any material or method mentioned.

摘要

目的

确定6至18岁年龄范围内角膜阻力因子（CRF）和角膜滞后量（CH）的分布及正常范围，以及它们与生物测量成分的关系。

地点

伊朗迪兹富勒。

设计

横断面研究。

方法

本研究对迪兹富勒学龄儿童采用多阶段、分层、整群抽样方法。所有学生均接受生物测量、非散瞳验光和角膜生物力学特性检查；所有病例的检查均按相同顺序进行。

结果

在864名入选学生中，683名参与了研究。CRF和CH的平均值分别为11.74 mmHg±1.77（标准差）（95%置信区间[CI]，11.58 - 11.89）和11.49±1.91 mmHg（95%CI，11.33 - 11.65）。在多元线性回归模型中，CRF与女性性别（β系数 = 0.488，P = 0.013）、中央角膜厚度（CCT）（β系数 = 0.034，P = 0.001）以及角膜曲率计测量值（β系数 = 0.157，P = 0.003）显著相关，CH与CCT（β系数 = 0.025，P < 0.001）、眼轴长度（β系数 = -0.303，P = 0.011）以及角膜曲率计测量值（β系数 = 0.11，P = 0.043）显著相关。年龄每增加一岁，峰值1面积减少42个单位（P = 0.003）。