Dharaiya Nisarg, Maitra Nandita
Department of Obstetrics and Gynecology, Baroda Medical College, Baroda, India.
J Obstet Gynaecol India. 2014 Aug;64(4):284-8. doi: 10.1007/s13224-014-0513-8. Epub 2014 Apr 12.
Cervical cancer is the most common cancer among Indian women. Only 5 % of women in developing countries have ever been screened for cervical abnormalities.
To study the correlation of cytology and colposcopy in VIA-positive women attending the Gynaecology clinic.
This prospective cross-sectional study on 200 symptomatic women compares the role of cytology and colposcopy in the assessment of subjects testing positive for acetowhite lesions on the cervix after application of 5 % acetic acid (VIA).
200/637 women screened in OPD tested VIA positive, giving a positivity rate of 31 %. Six smears were reported as LGSIL or HGSIL giving a cytological abnormality rate of 3 %. The association between cytology and Reid's score was statistically significant at a p value of 0.02. Of the 4 cases with biopsy-confirmed invasive cancer, cytology reported 2 as LGSIL and 2 as HGSIL. Colposcopy reported all these women as CIN 2/3.
The accuracies of Pap smear cytology and colposcopy in the diagnosis of precancerous and cancerous lesions of cervix were good.
宫颈癌是印度女性中最常见的癌症。发展中国家只有5%的女性曾接受过宫颈异常筛查。
研究在妇科门诊就诊的醋酸肉眼观察法(VIA)阳性女性中细胞学检查与阴道镜检查的相关性。
这项针对200名有症状女性的前瞻性横断面研究比较了细胞学检查和阴道镜检查在评估应用5%醋酸后宫颈醋酸白病变检测呈阳性的受试者中的作用。
在门诊筛查的637名女性中,200名VIA检测呈阳性,阳性率为31%。6份涂片报告为低度鳞状上皮内病变(LGSIL)或高度鳞状上皮内病变(HGSIL),细胞学异常率为3%。细胞学检查与Reid评分之间的关联在p值为0.02时具有统计学意义。在4例活检确诊为浸润癌的病例中,细胞学检查报告2例为LGSIL,2例为HGSIL。阴道镜检查将所有这些女性报告为宫颈上皮内瘤变2/3级(CIN 2/3)。
巴氏涂片细胞学检查和阴道镜检查在诊断宫颈癌前病变和癌性病变方面准确性良好。