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基于颊部柔韧性提出的口腔黏膜下纤维化新分级

Proposed new grading of oral submucous fibrosis based on cheek flexibility.

作者信息

Patil Santosh, Maheshwari Sneha

机构信息

Dept of Oral Medicine and Radiology, Chattisgarh Dental College and Research Institute, Rajnandgaon (Chattisgarh).

Dental Practitioner, Jodhpur (Raj), India.

出版信息

J Clin Exp Dent. 2014 Jul 1;6(3):e255-8. doi: 10.4317/jced.51378. eCollection 2014 Jul.

Abstract

OBJECTIVES

Oral submucous fibrosis (OSMF) is a potentially malignant disorder of oral cavity, pharynx and upper digestive tract, characterized by progressive inability to open the mouth. Based on clinical and/or histopathological features, various classifications and grading systems have been put forth till date. The aim of the present study was to study the variance in cheek flexibility in OSMF patients, the observance of which led to the introduction of a new grading for the condition.

MATERIAL AND METHODS

The study included 412 patients with OSMF attending to the Department of Oral Medicine and Radiology during the period from December 2008 to June 2013. A detailed history and examination of the patients was performed with special emphasis on measuring cheek flexibility. Statistical analysis was done using Chi-square test and p<0.05 was considered to be statistically significant.

RESULTS

The most common etiological factor was tobacco (73.3%). All the patients reported with burning sensation of the mouth and blanching of the mucosa. Malignancy was reported in only 4.6% patients. 60.4% patients showed cheek flexibility of 30mm and above, while 29.6% patients showed cheek flexibility between 20-30mm and 10% patients showed less than 30mm of cheek flexibility.

CONCLUSION

The observations of the present study have led to the proposal of a new grading of OSMF based on cheek flexibility which could assist in the categorization of the condition by the clinicians. Key words:Cheek flexibility, oral submucous fibrosis, grading, areca nut.

摘要

目的

口腔黏膜下纤维化(OSMF)是口腔、咽和上消化道的一种潜在恶性疾病,其特征为开口逐渐受限。基于临床和/或组织病理学特征,迄今为止已提出了各种分类和分级系统。本研究的目的是研究OSMF患者颊部柔韧性的差异,基于此观察结果引入了一种新的病情分级。

材料与方法

本研究纳入了2008年12月至2013年6月期间到口腔医学与放射科就诊的412例OSMF患者。对患者进行了详细的病史询问和检查,特别着重于测量颊部柔韧性。采用卡方检验进行统计分析,p<0.05被认为具有统计学意义。

结果

最常见的病因是烟草(73.3%)。所有患者均有口腔烧灼感和黏膜变白的症状。仅4.6%的患者报告有恶变情况。60.4%的患者颊部柔韧性≥30mm,29.6%的患者颊部柔韧性在20 - 30mm之间,10%的患者颊部柔韧性<20mm。

结论

本研究的观察结果促使基于颊部柔韧性提出了一种新的OSMF分级,这有助于临床医生对病情进行分类。关键词:颊部柔韧性;口腔黏膜下纤维化;分级;槟榔

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