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槟榔咀嚼者与口腔黏膜下纤维化患者唾液流速和pH值的评估:一项对比研究。

Assessment of Salivary Flow Rate and pH Among Areca Nut Chewers and Oral Submucous Fibrosis Subjects: A Comparative Study.

作者信息

Abdul Khader Nishat Fatima, Dyasanoor Sujatha

机构信息

Department of Oral Medicine, The Oxford Dental College and Research Hospital, Bangalore, India ; Department of Radiology, The Oxford Dental College and Research Hospital, Bangalore, India.

Department of Oral Medicine, The Oxford Dental College and Research Hospital, Bangalore, India ; Department of Maxillofacial Radiology, The Oxford Dental College and Research Hospital, Bangalore, India.

出版信息

J Cancer Prev. 2015 Sep;20(3):208-15. doi: 10.15430/JCP.2015.20.3.208.

Abstract

BACKGROUND

To assess and compare the salivary flow rate (SFR) and salivary pH among areca nut chewers, oral submucous fibrosis (OSMF) patients and apparently healthy individuals.

METHODS

A comparative study was conducted to assess and compare the SFR and pH among 135 outpatients (45 areca nut chewers + 45 OSMF + 45 control) at The Oxford Dental College and Research Hospital, Bangalore, India. Subjects were interviewed using structural proforma and Modified Schirmer strips and pH paper were implemented for assessing SFR and pH respectively. Statistical analysis was done using IBM SPSS ver. 21.0 software.

RESULTS

A statistically significant increase in SFR (35.7 mm at 3rd minutes) among areca nut group and a decrease in SFR among OSMF group (23.4 mm at 3rd minutes) when compared to apparently healthy subjects (30.7 mm at 3rd minutes). The mean pH among areca nut, OSMF and control groups was 6.76, 6.82, and 6.74 respectively with no statistical significance.

CONCLUSIONS

The observation and findings of the study clearly showed hypersalivation among areca nut group and hyposalivation among OSMF group, with no significant change in salivary pH when compared to healthy subjects.

摘要

背景

评估并比较槟榔咀嚼者、口腔黏膜下纤维化(OSMF)患者和健康个体的唾液流速(SFR)及唾液pH值。

方法

在印度班加罗尔的牛津牙科学院及研究医院,对135名门诊患者(45名槟榔咀嚼者 + 45名OSMF患者 + 45名对照者)进行了一项比较研究,以评估和比较其SFR和pH值。使用结构化表格对受试者进行访谈,并分别采用改良式Schirmer试纸条和pH试纸评估SFR和pH值。使用IBM SPSS 21.0软件进行统计分析。

结果

与健康受试者(第3分钟时为30.7毫米)相比,槟榔组的SFR(第3分钟时为35.7毫米)有统计学显著升高,而OSMF组的SFR(第3分钟时为23.4毫米)降低。槟榔组、OSMF组和对照组的平均pH值分别为6.76、6.82和6.74,无统计学差异。

结论

该研究的观察结果和发现清楚地表明,槟榔组唾液分泌过多,OSMF组唾液分泌过少,与健康受试者相比,唾液pH值无显著变化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/af51/4597810/d49e33e793b7/jcp-20-208f1.jpg

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