Suppr超能文献

互联网上的新药:卡芬他明的案例。

New drugs on the Internet: the case of Camfetamine.

作者信息

Cinosi Eduardo, Corazza Ornella, Santacroce Rita, Lupi Matteo, Acciavatti Tiziano, Martinotti Giovanni, di Giannantonio Massimo

机构信息

Neuroscience and Imaging Department, Chair of Psychiatry, "G. d'Annunzio" University, Via dei Vestini 131, 66100 Chieti, Italy ; School of Life and Medical Sciences, University of Hertfordshire, College Lane, AL10 9AB Hatfield, UK.

School of Life and Medical Sciences, University of Hertfordshire, College Lane, AL10 9AB Hatfield, UK.

出版信息

Biomed Res Int. 2014;2014:419026. doi: 10.1155/2014/419026. Epub 2014 Jul 16.

Abstract

INTRODUCTION

The number of new psychoactive substances (NPS) advertised for sale online is constantly increasing and it has become a phenomenon of global concern. Among NPS, Camfetamine has been rediscovered as recreational drug in 2011. Very little information is still available in the scientific literature on its nature and potential health risks.

METHODS

Data in scientific literature were integrated with a multilingual qualitative assessment of a range of online resources over the period of 32 months (May 2011-January 2014).

RESULTS

N-Methyl-3-phenyl-norbornan-2-amine (Camfetamine) may act as an indirect dopaminergic agonist in the central nervous system and may have mild-moderate opioid activity too. There are no current epidemiological data about recreational use of Camfetamine; our research shows that it is indeed used especially by individuals with a history of recreational polydrug misuse. It facilitates mental alertness, induces relaxation, and, unlike many other stimulants, seems not to be associated with severe physical effects. Valid causes for concern issued in our research may be Camfetamine intravenous or intramuscular administration as well as its use in conjunction with other psychoactive substances.

CONCLUSIONS

It is here highlighted that more large-scale studies need to be carried out to confirm and better describe both the extent of Camfetamine misuse and possible psychotropic/adverse effects.

摘要

引言

在网上售卖的新型精神活性物质(NPS)数量不断增加,已成为全球关注的现象。在新型精神活性物质中,卡芬他明于2011年被重新发现为一种消遣性药物。关于其性质和潜在健康风险,科学文献中仍鲜有信息。

方法

将科学文献中的数据与对一系列在线资源在32个月(2011年5月至2014年1月)期间进行的多语言定性评估相结合。

结果

N-甲基-3-苯基降冰片-2-胺(卡芬他明)可能在中枢神经系统中作为间接多巴胺能激动剂起作用,也可能具有轻度至中度阿片样物质活性。目前没有关于卡芬他明消遣性使用的流行病学数据;我们的研究表明,它确实被有消遣性多种药物滥用史的人使用。它能促进精神警觉,诱导放松,而且与许多其他兴奋剂不同,似乎与严重的身体影响无关。我们的研究中提出的令人担忧的合理原因可能是卡芬他明的静脉或肌肉注射给药以及它与其他精神活性物质的联合使用。

结论

在此强调,需要开展更多大规模研究,以确认并更好地描述卡芬他明滥用的程度以及可能的精神/不良反应。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验