Balint G A
East Afr Med J. 1989 Aug;66(8):535-7.
It seems that endogenous prostacyclin is one of the most important natural protective substances in the (human) gastroduodenal mucosa. According to the observations, in humans there is a definite tendency toward decreased endogenous prostacyclin production in the gastroduodenal mucosa of smokers. This phenomenon draws attention to the possible role of smoking in the development of peptic ulcer disease.
内源性前列环素似乎是（人类）胃十二指肠黏膜中最重要的天然保护物质之一。根据观察，在人类中，吸烟者胃十二指肠黏膜内源性前列环素的产生有明确的减少趋势。这一现象使人们关注吸烟在消化性溃疡疾病发生中的可能作用。
