循环肿瘤细胞的分子特征：个性化癌症治疗的圣杯？ - Suppr

Molecular characterization of circulating tumor cells: Holy Grail for personalized cancer treatment?

作者信息

Lianidou Evi S

机构信息

Analysis of Circulating Tumor Cells (ACTC) Lab, Laboratory of Analytical Chemistry, Department of Chemistry, University of Athens, Athens, Greece.

出版信息

Clin Chem. 2014 Oct;60(10):1249-51. doi: 10.1373/clinchem.2014.230144. Epub 2014 Aug 20.

DOI:10.1373/clinchem.2014.230144

PMID:25142245

Abstract

摘要

相似文献

Molecular characterization of circulating tumor cells: Holy Grail for personalized cancer treatment?循环肿瘤细胞的分子特征：个性化癌症治疗的圣杯？

Clin Chem. 2014 Oct;60(10):1249-51. doi: 10.1373/clinchem.2014.230144. Epub 2014 Aug 20.

Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purified circulating tumor cells from patients with metastatic breast cancer.对转移性乳腺癌患者经流式细胞分选纯化的单个CK阳性/CD45阴性循环肿瘤细胞进行基因组高分辨率分析。

Clin Chem. 2014 Oct;60(10):1290-7. doi: 10.1373/clinchem.2014.222331.

ERCC1-positive circulating tumor cells in the blood of ovarian cancer patients as a predictive biomarker for platinum resistance.卵巢癌患者血液中ERCC1阳性循环肿瘤细胞作为铂类耐药的预测生物标志物。

Clin Chem. 2014 Oct;60(10):1282-9. doi: 10.1373/clinchem.2014.224808. Epub 2014 Jul 11.

ERCC1-expressing circulating tumor cells as a potential diagnostic tool for monitoring response to platinum-based chemotherapy and for predicting post-therapeutic outcome of ovarian cancer.表达ERCC1的循环肿瘤细胞作为监测铂类化疗反应和预测卵巢癌治疗后结局的潜在诊断工具。

Oncotarget. 2017 Apr 11;8(15):24303-24313. doi: 10.18632/oncotarget.13286.

Detection of TP53/PIK3CA Mutations in Cell-Free Plasma DNA From Metastatic Breast Cancer Patients Using Next Generation Sequencing.使用下一代测序技术检测转移性乳腺癌患者游离血浆DNA中的TP53/PIK3CA突变

Clin Breast Cancer. 2016 Oct;16(5):418-423. doi: 10.1016/j.clbc.2016.05.004. Epub 2016 May 14.

Using circulating tumor cells to guide therapy in breast cancer: could this replace biopsies?利用循环肿瘤细胞指导乳腺癌治疗：这能否取代活检？

Pharmacogenomics. 2015;16(7):669-72. doi: 10.2217/pgs.15.36. Epub 2015 May 7.

Establishment of a New Ovarian Cancer Cell Line CA5171.新型卵巢癌细胞系CA5171的建立

Reprod Sci. 2015 Jun;22(6):725-34. doi: 10.1177/1933719114557893. Epub 2014 Nov 12.

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen.循环游离DNA突变作为接受他莫昔芬治疗的乳腺癌患者的生物标志物。

Oncotarget. 2016 Jul 12;7(28):43412-43418. doi: 10.18632/oncotarget.9727.

Circulating-free DNA Mutation Associated with Response of Targeted Therapy in Human Epidermal Growth Factor Receptor 2-positive Metastatic Breast Cancer.循环游离DNA突变与人类表皮生长因子受体2阳性转移性乳腺癌靶向治疗反应的相关性

Chin Med J (Engl). 2017 Mar 5;130(5):522-529. doi: 10.4103/0366-6999.200542.

[ERCC1 as a Marker of Ovarian Cancer Resistance to Platinum Drugs].[ERCC1作为卵巢癌对铂类药物耐药性的标志物]

Antibiot Khimioter. 2015;60(3-4):42-50.

引用本文的文献

Molecular characterization of circulating tumour cells identifies predictive markers for outcome in primary, triple-negative breast cancer patients.循环肿瘤细胞的分子特征可识别原发性三阴性乳腺癌患者预后的预测标志物。

J Cell Mol Med. 2020 Aug;24(15):8405-8416. doi: 10.1111/jcmm.15349. Epub 2020 Jun 18.

CXCR4 and JUNB double-positive disseminated tumor cells are detected frequently in breast cancer patients at primary diagnosis.在乳腺癌患者初诊时，经常检测到CXCR4和JUNB双阳性的播散性肿瘤细胞。

Ther Adv Med Oncol. 2020 Apr 28;12:1758835919895754. doi: 10.1177/1758835919895754. eCollection 2020.

Circulating tumor cell isolation, culture, and downstream molecular analysis.循环肿瘤细胞的分离、培养和下游分子分析。

Biotechnol Adv. 2018 Jul-Aug;36(4):1063-1078. doi: 10.1016/j.biotechadv.2018.03.007. Epub 2018 Mar 17.

Direct comparison study of DNA methylation markers in EpCAM-positive circulating tumour cells, corresponding circulating tumour DNA, and paired primary tumours in breast cancer.EpCAM阳性循环肿瘤细胞、相应循环肿瘤DNA及配对原发性乳腺癌肿瘤中DNA甲基化标志物的直接比较研究

Oncotarget. 2017 Jun 27;8(42):72054-72068. doi: 10.18632/oncotarget.18679. eCollection 2017 Sep 22.

Droplet digital PCR of circulating tumor cells from colorectal cancer patients can predict KRAS mutations before surgery.对结直肠癌患者循环肿瘤细胞进行液滴数字PCR可在手术前预测KRAS突变。

Mol Oncol. 2016 Oct;10(8):1221-31. doi: 10.1016/j.molonc.2016.05.009. Epub 2016 Jun 7.

Current Understanding of Circulating Tumor Cells - Potential Value in Malignancies of the Central Nervous System.循环肿瘤细胞的当前认识——在中枢神经系统恶性肿瘤中的潜在价值

Front Neurol. 2015 Aug 10;6:174. doi: 10.3389/fneur.2015.00174. eCollection 2015.

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Molecular characterization of circulating tumor cells: Holy Grail for personalized cancer treatment?

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