Chen Y-J A, Tseng J-J, Yang M-J, Tsao Y-P, Lin H-Y
Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Taichung, Taiwan.
Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan.
Lupus. 2014 Dec;23(14):1528-32. doi: 10.1177/0961203314548713. Epub 2014 Aug 21.
When the disease activity of systemic lupus erythematosus (SLE) is controlled appropriately, a pregnant woman who has lupus is able to carry safely to term and deliver a healthy infant. While the physiology of a healthy pregnancy itself influences ventilatory function, acute pulmonary distress may decrease oxygenation and influence both mother and fetus. Though respiratory failure in pregnancy is relatively rare, it remains one of the leading conditions requiring intensive care unit admission in pregnancy and carries a high risk of maternal and fetal morbidity and mortality, not to mention the complexity caused by lupus flare. We report a case of SLE complicated with lupus pneumonitis and followed by acute respiratory distress during pregnancy. Though there is a high risk of maternal and fetal morbidity and mortality, maternal respiratory function improved after cesarean section and treatment of the underlying causes. The newborn had an extremely low birth weight but was well at discharge.
当系统性红斑狼疮(SLE)的疾病活动得到适当控制时,患有狼疮的孕妇能够安全地足月分娩并产下健康的婴儿。虽然健康妊娠本身的生理状况会影响通气功能,但急性肺窘迫可能会降低氧合并影响母亲和胎儿。尽管妊娠期间呼吸衰竭相对少见,但它仍然是需要入住重症监护病房的主要妊娠相关病症之一,并且母婴发病率和死亡率很高,更不用说狼疮发作所带来的复杂性了。我们报告一例SLE合并狼疮肺炎并在妊娠期间继发急性呼吸窘迫的病例。尽管母婴发病率和死亡率很高,但剖宫产及对潜在病因进行治疗后,母亲的呼吸功能得到了改善。新生儿出生体重极低,但出院时情况良好。