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准分子激光原位角膜磨镶术中使用机械角膜刀和飞秒激光后撕裂的板层角膜。

Tear menisci after laser in situ keratomileusis with mechanical microkeratome and femtosecond laser.

机构信息

School of Ophthalmology and Optometry, Wenzhou Medical University, Wenzhou, Zhejiang, China.

Affiliated Hospital of Nantong University, Nantong, Jiangsu, China.

出版信息

Invest Ophthalmol Vis Sci. 2014 Aug 21;55(9):5806-12. doi: 10.1167/iovs.13-13669.

Abstract

PURPOSE

To investigate the effect on tear menisci after laser in situ keratomileusis (LASIK) with flap creation by either microkeratome or femtosecond laser.

METHODS

Sixty eyes of 30 myopes were analyzed. Fifteen patients underwent LASIK with Moria II microkeratome, and the other 15 patients with 60-KHz IntraLase femtosecond laser. Upper and lower tear meniscus parameters of height (UTMH, LTMH) and area (UTMA, LTMA) were measured by SD-OCT preoperatively and 1 week, 1 month, and 3 months postoperatively.

RESULTS

Compared with the baseline values, all tear meniscus parameters decreased significantly at each postoperative time point (all P < 0.01) in both groups. LTMH increased significantly between 1 week and 1 month and between 1 and 3 months after surgery in the microkeratome (both P < 0.01) and femtosecond laser groups (P < 0.01, P = 0.012, respectively). There were significant increases in LTMA between 1 week and 1 month after surgery in the microkeratome group (P < 0.01) and in the femtosecond laser group (P = 0.028). There were no significant differences in UTMH, UTMA, LTMH, or LTMA between two groups. The depth of ablation was negatively correlated with the LTMA at 1 week after surgery (R = -0.256, P = 0.049) for all patients.

CONCLUSIONS

There were no significant differences in the tear meniscus parameters between the microkeratome and femtosecond laser groups. The depth of ablation was significantly correlated with the LTMA only at 1 week after surgery.

摘要

目的

研究微型角膜刀和飞秒激光制瓣的 LASIK 术后泪膜半月的影响。

方法

分析 30 例近视患者的 60 只眼。15 例患者接受 Moria II 微型角膜刀 LASIK,15 例患者接受 60-KHz IntraLase 飞秒激光。术前及术后 1 周、1 个月和 3 个月,用 SD-OCT 测量上下泪膜半月高度(UTMH、LTMH)和面积(UTMA、LTMA)参数。

结果

两组术后各时间点与术前相比,所有泪膜半月参数均显著下降(均 P < 0.01)。微型角膜刀组术后 1 周和 1 个月、1 个月和 3 个月时 LTMH 显著增加(均 P < 0.01),飞秒激光组术后 1 周和 1 个月时 LTMH 显著增加(均 P < 0.01,P = 0.012)。微型角膜刀组术后 1 周时 LTMA 显著增加(P < 0.01),飞秒激光组术后 1 周和 1 个月时 LTMA 显著增加(均 P < 0.01)。两组间 UTMH、UTMA、LTMH 和 LTMA 无显著差异。所有患者术后 1 周时,切削深度与 LTMA 呈负相关(R = -0.256,P = 0.049)。

结论

微型角膜刀与飞秒激光组的泪膜半月参数无显著差异。仅在术后 1 周时,切削深度与 LTMA 显著相关。

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