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十五年后,抗蠕虫药耐药性在瓜德罗普岛的山羊养殖场中急剧蔓延。

Fifteen years later, anthelmintic resistances have dramatically spread over goat farms in Guadeloupe.

作者信息

Mahieu Maurice, Ferré Benjamin, Madassamy Marylène, Mandonnet Nathalie

机构信息

INRA, UR143 Recherches Zootechniques, Domaine Duclos, F-97170 Petit bourg, Guadeloupe, France.

INRA, UR143 Recherches Zootechniques, Domaine Duclos, F-97170 Petit bourg, Guadeloupe, France; Cabricoop, Rond Point Destrellan, F-97122 Baie mahault, Guadeloupe, France.

出版信息

Vet Parasitol. 2014 Sep 15;205(1-2):379-84. doi: 10.1016/j.vetpar.2014.07.029. Epub 2014 Aug 12.

DOI:10.1016/j.vetpar.2014.07.029
PMID:25149098
Abstract

Faecal egg count reduction tests (FECRTs) were performed on 21 goat farms in Guadeloupe (FWI). Anthelmintic resistance (AR) to netobimin (benzimidazole) was found in all 15 herds in which it was tested. AR to ivermectin (avermectin) and levamisole (imidazothiazole) were also very largely spread (14 out of 17 farms and 7 out of 9 farms, respectively). AR to the final moxidectin (milbemycin) released was already present in 2 out of 9 farms in which it was tested. Haemonchus was the dominant genus of gastrointestinal nematodes and was more frequently found to be resistant to netobimin, ivermectin and moxidectin than Trichostrongylus, the latter appeared to be more often resistant to levamisole. A first survey 15 years ago revealed only AR to benzimidazoles and one suspected case of AR to ivermectin.

摘要

在瓜德罗普岛(法属西印度群岛)的21个山羊养殖场进行了粪便虫卵计数减少试验(FECRTs)。在所检测的15个畜群中,均发现了对奈托比明(苯并咪唑类)的抗蠕虫药耐药性(AR)。对伊维菌素(阿维菌素类)和左旋咪唑(咪唑并噻唑类)的耐药性也广泛存在(分别在17个养殖场中的14个以及9个养殖场中的7个被检测到)。在所检测的9个养殖场中,已有2个出现了对最终投放的莫昔克丁(米尔倍霉素)的耐药性。血矛线虫是胃肠道线虫的主要种类,相较于毛圆线虫,它对奈托比明、伊维菌素和莫昔克丁的耐药性更为常见,而后者似乎对左旋咪唑的耐药性更为常见。15年前的首次调查仅发现了对苯并咪唑类的耐药性以及1例疑似对伊维菌素耐药的病例。

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