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哮喘治疗中的综合疗法概述。

An overview of integrative therapies in asthma treatment.

机构信息

Center for Integrative Medicine, University of Arizona, Tucson, AZ, USA,

出版信息

Curr Allergy Asthma Rep. 2014 Oct;14(10):464. doi: 10.1007/s11882-014-0464-2.

DOI:10.1007/s11882-014-0464-2
PMID:25149166
Abstract

Treatment of asthma lends itself to an integrative medicine approach due to the multifactorial nature of the disease. It is well established that asthma has a neuromuscular component (bronchospasm), an immunological component (inflammation), and a psychological component. This encourages the use of diverse approaches to address all avenues of pathophysiology, aiming for the most effective blend of treatment approaches possible. Integrative medicine is defined by NIH NCCAM ( http://nccam.nih.gov ) as medicine that blends the use of evidence-based complementary therapies with conventional medicine. Statistics from the 2007 National Health Interview Survey (NHIS), conducted by the Centers for Disease Control and Prevention's (CDC) National Center for Health Statistics (NCHS), showed that approximately four out of 10 adults and approximately one in nine children and more than 50 % of children living with chronic illness, including asthma, used complementary therapies in the USA in 2007. Asthma and allergies rank among the top 15 most common medical conditions in which integrative therapies are used in both children and adults. To date, integrative treatment approaches with some evidence for benefit in asthma treatment include the following: nutrition modification, mind-body medicine, physical activity, and certain dietary supplement interventions.

摘要

由于哮喘的多因素性质,其治疗方法适合采用整体医学方法。众所周知,哮喘有神经肌肉成分(支气管痉挛)、免疫成分(炎症)和心理成分。这鼓励使用多种方法来解决所有病理生理学途径,旨在尽可能有效地融合治疗方法。美国国立卫生研究院补充和整合医学中心(NIH NCCAM,http://nccam.nih.gov)将整体医学定义为将循证补充疗法与常规医学结合使用的医学。疾病控制和预防中心(CDC)国家卫生统计中心(NCHS)进行的 2007 年全国健康访谈调查(NHIS)的统计数据显示,2007 年,美国约有十分之四的成年人、约十分之一的儿童和超过 50%的患有慢性病(包括哮喘)的儿童使用补充疗法。哮喘和过敏在儿童和成人中使用整体疗法的前 15 种最常见医疗条件中排名靠前。迄今为止,在哮喘治疗中具有一定益处证据的整体治疗方法包括以下几种:营养调整、身心医学、身体活动和某些膳食补充剂干预。

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Int J Chron Obstruct Pulmon Dis. 2024 Oct 16;19:2309-2320. doi: 10.2147/COPD.S475714. eCollection 2024.
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Asthma: New Integrative Treatment Strategies for the Next Decades.哮喘:未来几十年的新综合治疗策略。
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Exercise and Asthma.运动与哮喘。

本文引用的文献

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Parameters of lung inflammation in asthmatic as compared to healthy children in a contaminated city.哮喘患儿与污染城市健康儿童肺部炎症参数比较。
BMC Pulm Med. 2014 Jul 8;14:111. doi: 10.1186/1471-2466-14-111.
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Psychological stress and asthma: a new enemy within.心理压力与哮喘:体内的新敌人。
Int Arch Allergy Immunol. 2014;164(2):109-11. doi: 10.1159/000363447. Epub 2014 Jun 14.
3
Airway and systemic oxidant-antioxidant dysregulation in asthma: a possible scenario of oxidants spill over from lung into blood.哮喘中气道和全身氧化-抗氧化失衡:一种氧化剂从肺溢出到血液的可能情况。
Adv Exp Med Biol. 2020;1228:369-380. doi: 10.1007/978-981-15-1792-1_25.
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Determinants for asthma control, quality of life and use of complementary and alternative medicine in asthmatic pediatric patients in four cities.哮喘患儿控制情况、生活质量及使用补充和替代医学的决定因素。
World J Pediatr. 2018 Oct;14(5):482-491. doi: 10.1007/s12519-018-0167-1. Epub 2018 Jul 25.
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Integrative Medicine for Respiratory Conditions: Asthma and Chronic Obstructive Pulmonary Disease.呼吸系统疾病的整合医学:哮喘与慢性阻塞性肺疾病
Med Clin North Am. 2017 Sep;101(5):925-941. doi: 10.1016/j.mcna.2017.04.008. Epub 2017 Jun 21.
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Nutritional status and physical inactivity in moderated asthmatics: A pilot study.中度哮喘患者的营养状况与身体活动不足:一项试点研究。
Medicine (Baltimore). 2016 Aug;95(31):e4485. doi: 10.1097/MD.0000000000004485.
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Morin Attenuates Ovalbumin-Induced Airway Inflammation by Modulating Oxidative Stress-Responsive MAPK Signaling.桑色素通过调节氧化应激反应性丝裂原活化蛋白激酶信号通路减轻卵清蛋白诱导的气道炎症。
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Effects of early-life exposure to allergens and bacteria on recurrent wheeze and atopy in urban children.早年接触过敏原和细菌对城市儿童复发性喘息和特应性的影响。
J Allergy Clin Immunol. 2014 Sep;134(3):593-601.e12. doi: 10.1016/j.jaci.2014.04.018. Epub 2014 Jun 4.
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Work-related psychosocial stress as a risk factor for asthma, allergy, and respiratory infections in the Swedish workforce.工作相关的社会心理压力作为瑞典劳动力中哮喘、过敏和呼吸道感染的一个风险因素。
Psychol Rep. 2014 Apr;114(2):377-89. doi: 10.2466/15.14.PR0.114k20w3.
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Antioxidant defense enzyme genes and asthma susceptibility: gender-specific effects and heterogeneity in gene-gene interactions between pathogenetic variants of the disease.抗氧化防御酶基因与哮喘易感性:疾病致病变异之间基因-基因相互作用的性别特异性效应和异质性
Biomed Res Int. 2014;2014:708903. doi: 10.1155/2014/708903. Epub 2014 May 5.
7
Effect of vitamin D3 on asthma treatment failures in adults with symptomatic asthma and lower vitamin D levels: the VIDA randomized clinical trial.维生素 D3 对有症状的哮喘且维生素 D 水平较低的成年哮喘治疗失败的影响:VIDA 随机临床试验。
JAMA. 2014 May;311(20):2083-91. doi: 10.1001/jama.2014.5052.
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Omega-3 fatty acids and asthma in children.ω-3 脂肪酸与儿童哮喘。
Allergy Asthma Proc. 2014 May-Jun;35(3):233-40. doi: 10.2500/aap.2014.35.3736.
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Immunoregulatory mechanisms of vitamin D relevant to respiratory health and asthma.维生素 D 与呼吸健康和哮喘相关的免疫调节机制。
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