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晚期腹部肿瘤患者的肠梗阻管理

Intestinal obstruction management in patients with advanced abdominal neoplasia.

作者信息

Simion L, Straja Nd, Alecu M, Poroch V, Moşoiu D, Panti C, Grigorean V, Brătucu E

出版信息

Chirurgia (Bucur). 2014 Jul-Aug;109(4):527-33.

Abstract

BACKGROUND

The present study describes the difficulties encountered in the diagnostic process and treatment of intestinal obstruction developed by patients with advanced abdominal neoplasia.

METHODS

This unicentric and retrospective study evaluates patients suffering from intestinal occlusion operated on at the First Surgical Clinic of the Oncology Institute in Bucharest, over a period of 4 years (2010 - 2013). Of these, 61 cases in which the occlusion occurred on the background of an advanced abdominal neoplasia were selected. We considered as advanced those cases of abdominal cancer where curative oncologic treatment is no longer possible due to the evolution stage.

RESULTS

The random selection of the study period, the introduction of all the patients identified with this type of pathology, as well as the concentration of advanced abdominal neoplasia at the Oncology Institute in Bucharest are the elements that allow us to state that the results of this study are representative. Particularities related to the clinical aspects of the intestinal occlusion in these patients, as well as difficulties in establishing the correct diagnosis were encountered.Surgical cure of the occlusion, with palliative aim of course,was possible in only 47 cases (representing 77.05%).

CONCLUSIONS

A standard treatment course cannot be devised for this type of patients. Palliative care, indispensable in cases of advanced neoplastic disease, remains the sole therapeutic method available for patients with no surgical cure for the obstruction. The main objective, for the entire study lot, was to ensure an as high as possible quality of life,a factor we must bear in mind as often as possible when choosing a surgical solution. Of course, when surgical treatment can be applied, overcoming the occlusive episode prolongs these patients' life and can even allow for other courses of complementary treatment to be undertaken.

摘要

背景

本研究描述了晚期腹部肿瘤患者发生肠梗阻时在诊断过程和治疗中遇到的困难。

方法

这项单中心回顾性研究评估了在布加勒斯特肿瘤研究所第一外科诊所接受手术治疗的肠梗阻患者,研究时间跨度为4年(2010 - 2013年)。其中,选取了61例因晚期腹部肿瘤而发生肠梗阻的病例。我们将那些由于疾病进展阶段而无法进行根治性肿瘤治疗的腹部癌症病例视为晚期病例。

结果

研究时间段的随机选择、所有确诊为此类病理类型患者的纳入,以及布加勒斯特肿瘤研究所晚期腹部肿瘤病例的集中性,这些因素使我们能够宣称本研究结果具有代表性。我们遇到了与这些患者肠梗阻临床方面相关的特殊性,以及在确立正确诊断方面的困难。当然,以姑息为目的的肠梗阻手术治愈仅在47例患者中可行(占77.05%)。

结论

无法为这类患者设计出标准的治疗方案。姑息治疗在晚期肿瘤疾病中不可或缺,对于肠梗阻无法手术治愈的患者而言,仍是唯一可用的治疗方法。对于整个研究群体来说,主要目标是确保尽可能高的生活质量,这是我们在选择手术方案时必须时刻牢记的一个因素。当然,当可以应用手术治疗时,克服梗阻发作能够延长这些患者的生命,甚至还能允许进行其他辅助治疗疗程。

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