Reynolds G P, Ceasar P M, Ruthven C R, Sandler M
Clin Chim Acta. 1978 Mar 1;84(1-2):225-31. doi: 10.1016/0009-8981(78)90498-9.
Three-hour urinary output values of dopamine, noradrenaline, adrenaline, 2-phenylethylamine and p-tyramine were measured in normal volunteers who had been induced, by pretreatment with ammonium chloride or sodium bicarbonate, to excrete maximally acid or alkaline urine. There were significant effects on the excretion of dopamine, adrenaline and 2-phenylethylamine, inversely proportional to urinary pH value. Adrenaline output increased with increasing urinary flow rate. There was a significant correlation between urinary concentrations of 2-phenylethylamine and p-tyramine. These findings may have important clinical implications.
在正常志愿者中测量了多巴胺、去甲肾上腺素、肾上腺素、2-苯乙胺和对酪胺的三小时尿量值，这些志愿者通过氯化铵或碳酸氢钠预处理，使其排出最大酸性或碱性尿液。对多巴胺、肾上腺素和2-苯乙胺的排泄有显著影响，与尿液pH值成反比。肾上腺素排出量随尿流率增加而增加。2-苯乙胺和对酪胺的尿液浓度之间存在显著相关性。这些发现可能具有重要的临床意义。
