Chu Fu-Ling, Hsu Chung-Huei, Jeng Chii
Chang Gung University of Science and Technology, Taoyuan, Taiwan; Graduate Institute of Nursing, College of Nursing, Taipei Medical University, Taipei, Taiwan.
School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan.
Obes Res Clin Pract. 2015 Jul-Aug;9(4):328-35. doi: 10.1016/j.orcp.2014.08.001. Epub 2014 Aug 23.
In previous study, we found that in order to prevent MS in women aged <65 years, the cutoff points of obesity indicators should be lowered.
To investigate whether our proposed cutoff points of obesity indicators predict the occurrence of hypertension (HT), diabetes mellitus (DM), and hyperlipidemia in premenopausal women with greater sensitivity and specificity compared to reference cutoff points of obesity that are currently being used.
Using the database of the "2002 Survey on the Prevalence of Hypertension, Hyperglycemia and Hyperlipidemia in Taiwan" provided by the Bureau of Health Promotion, Taiwan as research material, data from 2270 premenopausal women aged 20-65 years were used for the analyses. The receiver-operating characteristic curves (ROC) of the body-mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR), and waist-to-height ratio (WHtR) were used to predict HT, DM, and hyperlipidemia.
Obesity is not a good predictor of the occurrence of hyperlipidemia in premenopausal women aged <65 years. However, our proposed cutoff points had greater sensitivity and specificity than did the reference cutoff points. To prevent the risk of HT and DM in premenopausal women, the cutoff points of obesity indicators should be reduced. The proposed values are as follows: a WHR of 0.79; a WC of 74.7 cm; a WHtR of 0.49; and a BMI of 22.3 kg/m(2).
在先前的研究中，我们发现为预防65岁以下女性患多发性硬化症，肥胖指标的临界值应降低。
探讨与目前使用的肥胖参考临界值相比，我们提出的肥胖指标临界值是否能更敏感、更特异地预测绝经前女性患高血压（HT）、糖尿病（DM）和高脂血症的情况。
以台湾健康促进局提供的“2002年台湾高血压、高血糖和高脂血症患病率调查”数据库为研究资料，对2270名20 - 65岁绝经前女性的数据进行分析。采用体重指数（BMI）、腰围（WC）、腰臀比（WHR）和腰高比（WHtR）的受试者工作特征曲线（ROC）来预测HT、DM和高脂血症。
肥胖并非65岁以下绝经前女性患高脂血症的良好预测指标。然而，我们提出的临界值比参考临界值具有更高的敏感性和特异性。为预防绝经前女性患HT和DM的风险，应降低肥胖指标的临界值。建议值如下：WHR为0.79；WC为74.7厘米；WHtR为0.49；BMI为22.3千克/平方米。
