Konyshkina T M
Zh Mikrobiol Epidemiol Immunobiol. 1989 Nov(11):67-71.
The influence of the cultures of 14 Staphylococcus aureus and Staphylococcus epidermidis strains on the capacity of factor C3b of the complement for mediating the adhesive reaction of human neutrophils was studied. In experiments with 5 out of 11 S. aureus strains the essential weakening of reactions was registered, while one of the strains considerably enhanced reactions. Out of 3 S. epidermidis strains, the weakening of C3b-dependent reaction was noted in one case. The activity of the cultures did not correlate with the gelatinase properties of staphylococci and was absent in all gelatinase-positive Pseudomonas aeruginosa strains. The model worked out by the authors may be used for studying the influence of bacterial metabolites and biologically active substances on the effector properties of factor C3b of the complement.
研究了14株金黄色葡萄球菌和表皮葡萄球菌培养物对补体C3b因子介导人中性粒细胞黏附反应能力的影响。在对11株金黄色葡萄球菌中的5株进行的实验中，观察到反应明显减弱，而其中一株菌株则显著增强了反应。在3株表皮葡萄球菌中，有1例观察到C3b依赖性反应减弱。培养物的活性与葡萄球菌的明胶酶特性无关，且在所有明胶酶阳性的铜绿假单胞菌菌株中均未观察到。作者建立的模型可用于研究细菌代谢产物和生物活性物质对补体C3b因子效应特性的影响。
