Department of Orthopedics, Xuanwu Hospital Capital Medical University, Beijing, China.
National Clinical Research Center for Geriatric Diseases, Beijing, China.
Aging Clin Exp Res. 2021 Jul;33(7):1947-1953. doi: 10.1007/s40520-020-01725-7. Epub 2020 Oct 12.
Malnutrition is a risk factor for postoperative infectious complications of elderly patients undergoing posterior lumbar arthrodesis. At present, there is no gold standard for nutrition screening tools. We analyzed the value of predicting infectious complications among elderly patients over 70 years undergoing posterior lumbar arthrodesis by comparing the MNA-SF and GNRI. Demographic data, anthropometric measurements, serum albumin, surgical data and the occurrence of infectious complications and LOS were collected. Mini Nutritional Assessment short form (MNA-SF), Geriatric Nutritional Risk Index (GNRI) were performed within 24 h before surgery. Multivariable logistic regression analyses were used to identify predictors of infectious complications. The discriminatory performances of GNRI and MNA-SF scores for the occurrence of infectious complications were determined by receiver operating characteristic curves (ROC) analyses and the area under the curve (AUC). The study included 252 patients with a median age of 76.82 ± 6.41 years (range 70-84 years), and 142 patients (56.3%) were female. There were no significant differences in infectious complications (p = 0.236) and LOS (p = 0.580) among different GNRI categories. 27.3% malnourished patients evaluated by the MNA-SF suffered from infectious complications and 10.1% patients at risk of malnourished had infectious complications. Those patients had statistically significant higher prevalence of infectious complications (p = 0.002) and longer LOS (p = 0.023) than well-nourished patients. Multivariable analysis revealed that preoperative malnutrition and at risk of malnourished by the MNA-SF was significantly associated with infections. The area under the curve (AUC) of MNA-SF was 0.754, which was significantly high than AUC of GNRI (0.623) (Delong's test, p = 0.033). This study demonstrated that MNA-SF is a simple and effective tool for predicting the risk of infectious complications in elderly patients undergoing posterior lumbar arthrodesis.
营养不良是老年患者后路腰椎融合术后感染性并发症的危险因素。目前,营养筛查工具尚无金标准。我们通过比较 MNA-SF 和 GNRI 分析了 70 岁以上后路腰椎融合术老年患者预测感染性并发症的价值。收集了人口统计学数据、人体测量学测量、血清白蛋白、手术数据以及感染性并发症和 LOS 的发生情况。在手术前 24 小时内进行了简易营养评估量表(MNA-SF)和老年营养风险指数(GNRI)。使用多变量逻辑回归分析确定感染性并发症的预测因子。通过接受者操作特征曲线(ROC)分析和曲线下面积(AUC)确定 GNRI 和 MNA-SF 评分对感染性并发症发生的判别性能。该研究共纳入 252 例患者,中位年龄为 76.82±6.41 岁(70-84 岁),142 例(56.3%)为女性。不同 GNRI 分类之间的感染性并发症(p=0.236)和 LOS(p=0.580)无显著差异。27.3%的 MNA-SF 评估营养不良患者发生感染性并发症,10.1%有营养不良风险的患者发生感染性并发症。这些患者感染性并发症的发生率显著更高(p=0.002),LOS 更长(p=0.023),与营养良好的患者相比。多变量分析显示,术前营养不良和 MNA-SF 有营养不良风险与感染显著相关。MNA-SF 的曲线下面积(AUC)为 0.754,明显高于 GNRI 的 AUC(0.623)(Delong 检验,p=0.033)。本研究表明,MNA-SF 是预测后路腰椎融合术老年患者感染性并发症风险的一种简单有效的工具。