Del Vecchio R, La Torre P, Cotugno M, Costarelli L
Minerva Chir. 1989 Dec 31;44(23-24):2421-6.
A case of primary adenocarcinoma of the duodenum associated with Recklinghausen's disease and Caroli's disease provides the opportunity to review the literature. Malignant tumours of the duodenum are extremely rare and even rarer is their association with R's and Caroli's diseases. It should not be forgotten that in Recklinghausen's disease gastro-intestinal involvement is possible. Caroli's disease is diagnosed anatomopathologically. Surgical resection remains the sole satisfactory treatment when the tumour has not spread locally or at a distance. If it has, treatment must be palliative.
一例十二指肠原发性腺癌合并雷克林霍增氏病（神经纤维瘤病）和卡罗里病（先天性肝内胆管扩张症）为回顾相关文献提供了契机。十二指肠恶性肿瘤极为罕见，而与雷克林霍增氏病和卡罗里病相关联的情况则更为罕见。不应忘记，在雷克林霍增氏病中，胃肠道有可能受累。卡罗里病通过解剖病理学诊断。当肿瘤尚未局部或远处扩散时，手术切除仍然是唯一令人满意的治疗方法。如果已经扩散，则治疗必须是姑息性的。
