阿拉伯利比亚民众国西部地区结核分枝杆菌菌株的原发性和获得性耐药性
Primary and acquired drug resistance in Mycobacterium tuberculosis strains in western region of Libyan Arab Jamahiriya.
作者信息
Elghoul M T, Joshi R M, Rizghalla T
机构信息
Department of Medical Microbiology and Immunology, Great Al-Fateh University of Medical Science, Tripoli, Libyan Arab Jamahiriya.
出版信息
Trop Geogr Med. 1989 Oct;41(4):304-8.
Drug resistance in Mycobacterium tuberculosis strains prevalent in the Western Region of Libyan Arab Jamahiriya was studied for the years 1984, 1985 and 1986 at the regional tuberculosis control centre at Gurgi, Tripoli. Records of resistance to streptomycin, isoniazid, ethambutol and rifampicin were analysed. Whereas primary drug resistance was observed in 5.1%, 19.5% and 3.8%, acquired drug resistance was found in 12.2%, 34.0% and 15.3% of the strains in 1984, 1985 and 1986 respectively. Only 3 out of 598 strains (1.2%) were found to show acquired resistance to rifampicin. No primary resistance to rifampicin was observed. The situation of drug resistance in pulmonary tuberculosis in the Jamahiriya is discussed.
1984年、1985年和1986年，在的黎波里古尔吉的地区结核病控制中心对阿拉伯利比亚民众国西部地区流行的结核分枝杆菌菌株的耐药性进行了研究。分析了对链霉素、异烟肼、乙胺丁醇和利福平的耐药记录。1984年、1985年和1986年，分别有5.1%、19.5%和3.8%的菌株观察到原发性耐药，12.2%、34.0%和15.3%的菌株发现获得性耐药。在598株菌株中，仅3株（1.2%）显示对利福平有获得性耐药。未观察到对利福平的原发性耐药。讨论了民众国肺结核的耐药情况。
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