Machado Bártoli I
G E N. 1989 Apr-Jun;43(2):116-9.
The Immunology in Gastric Cancer has slowly advanced during the past 20 years. Specific antigens have not been obtained although in a number of cases associated antigens such as alpha FP or CEA have been detected. In advanced cases the T cell immunological competence could be altered, however, compared to colorectal cancer this alteration is less significant. Serum factors seem to play an immunomodulatory role which might influence the variable response observed among the different groups of patients. In gastric cancer it seems essential to investigate the nature of those serum factors to further dissect abnormalities of T cell function.
在过去20年里，胃癌免疫学进展缓慢。尽管在一些病例中检测到了相关抗原，如甲胎蛋白或癌胚抗原，但尚未获得特异性抗原。在进展期病例中，T细胞免疫能力可能会发生改变，然而，与结直肠癌相比，这种改变不太明显。血清因子似乎发挥着免疫调节作用，这可能会影响不同患者群体中观察到的可变反应。在胃癌中，研究这些血清因子的性质对于进一步剖析T细胞功能异常似乎至关重要。
