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埃塞俄比亚地理上相距甚远的血吸虫病流行地区曼氏血吸虫感染率和感染强度的现状:一项比较研究

Status of Schistosoma mansoni prevalence and intensity of infection in geographically apart endemic localities of Ethiopia: a comparison.

作者信息

Aemero Mulugeta, Berhe Nega, Erko Berhanu

机构信息

Department of Biology, College of Natural & Computational Sciences, University of Gondar, Ethiopia.

Aklilu Lemma Institute of Pathobiology, College of Health Sciences, Addis Ababa University, Ethiopia.

出版信息

Ethiop J Health Sci. 2014 Jul;24(3):189-94. doi: 10.4314/ejhs.v24i3.1.

Abstract

BACKGROUND

Schistosomiasis is one of the chronic and neglected tropical diseases affecting rural communities. Heavy infections contribute to anemia and can retard children's growth, physical activity and cognitive function. This study was conducted in order to determine the prevalence, intensity and variation of Schistosoma mansoni infection among human subjects in geographically apart localities. The prevalence and intensity of Schistosoma mansoni infection was assessed in three geographically apart endemic areas of Ethiopia from May to August 2010 through cross-sectional approach.

METHODS

A total of 1073 individuals (528 males and 545 females) were found eligible for the study. Their age ranged from 5-60 years with mean age of 11 years in Wondo Genet, 22 years in Kemissie and 24 years in Sille-Elgo. Small plastic sheets were distributed to the study participants and sizable stool specimens were collected and examined using Kato-Katz method (41.7mg template).

RESULT

The prevalence of Schistosoma mansoni infection among the study participants in Kemissie, Wondo Genet and Sille-Elgo was 89.6%, 59.9%, and 31.6%, respectively. The highest geometric mean of egg per gram of stool for Kemissie, Wondo Genet and Sille-Elgo was, 5208 and 346, 8472 and 252, 3960 and 91, respectively.

CONCLUSION

It was observed that there was comparable variation in the prevalence and intensity of infection among the study localities. Moreover, it is indicated that S. mansoni is still an ongoing public health problem which requires integrated intervention activities in the country.

摘要

背景

血吸虫病是影响农村社区的慢性被忽视热带病之一。重度感染会导致贫血,并可能阻碍儿童生长、身体活动和认知功能。开展本研究是为了确定在地理位置不同的地区人类受试者中曼氏血吸虫感染的流行率、感染强度及差异。2010年5月至8月,通过横断面研究方法,对埃塞俄比亚三个地理位置不同的流行地区的曼氏血吸虫感染流行率和感染强度进行了评估。

方法

共1073人(528名男性和545名女性)符合研究条件。他们的年龄在5至60岁之间,在翁多杰内特平均年龄为11岁,在凯米西为22岁,在锡勒-埃尔戈为24岁。向研究参与者分发小塑料片,并收集足量粪便标本,采用加藤厚涂片法(41.7毫克模板)进行检测。

结果

在凯米西、翁多杰内特和锡勒-埃尔戈的研究参与者中,曼氏血吸虫感染率分别为89.6%、59.9%和31.6%。凯米西、翁多杰内特和锡勒-埃尔戈每克粪便虫卵的最高几何平均数分别为5208和346、8472和252、3960和91。

结论

观察发现,各研究地区的感染流行率和感染强度存在类似差异。此外,表明曼氏血吸虫仍是该国一个持续存在的公共卫生问题,需要开展综合干预活动。

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