Bascones-Martínez Antonio, Muñoz-Corcuera Marta, Bascones-Ilundain Jaime
Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontología, Universidad Complutense de Madrid, Madrid, España.
Med Clin (Barc). 2015 Jul 6;145(1):31-5. doi: 10.1016/j.medcli.2014.07.019. Epub 2014 Sep 3.
Diabetes mellitus is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, a defect in insulin action or a combination of both. Periodontitis is now considered a chronic localized infection of the oral cavity that can trigger inflammatory host immune responses at local and systemic levels, and can also be a source of bacteremia. It is now known that periodontitis has an influence on the pathogenesis of certain systemic diseases. The biological relationship between diabetes and periodontal disease is well documented. In the mid-90s sufficient scientific support for the association between diabetes and periodontitis was published, and periodontitis was designated as the sixth complication of diabetes. There have been studies that show an improvement in both clinical and immunological parameters of periodontitis and glycemic control in long-term diabetes after treatment of periodontal disease. In addition, scientific evidence confirms that poorer glycemic control contributes to a worse periodontal condition. The interplay between the 2 conditions highlights the importance of the need for a good communication between the internist and dentist about diabetic patients, considering always the possibility that the 2 diseases may be occurring simultaneously in order to ensure an early diagnosis of both.
糖尿病是一组代谢性疾病,其特征为因胰岛素分泌缺陷、胰岛素作用缺陷或两者兼而有之导致的高血糖。牙周炎现在被认为是一种口腔慢性局部感染,可在局部和全身水平引发宿主炎症免疫反应,并且也可能是菌血症的一个来源。现在已知牙周炎对某些全身性疾病的发病机制有影响。糖尿病与牙周病之间的生物学关系已有充分记录。在90年代中期,有足够的科学依据支持糖尿病与牙周炎之间的关联被发表,并且牙周炎被指定为糖尿病的第六种并发症。有研究表明,在牙周病治疗后,长期糖尿病患者的牙周炎临床和免疫参数以及血糖控制均有改善。此外,科学证据证实血糖控制较差会导致牙周状况更糟。这两种情况之间的相互作用凸显了内科医生和牙医就糖尿病患者进行良好沟通的必要性,始终要考虑到这两种疾病可能同时发生的可能性,以便确保对两者都能进行早期诊断。