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[间歇性腹膜透析:六年经验]

[Intermittent peritoneal dialysis: a 6 years' experience].

作者信息

García-Ortiz R, Gómez M, Olea C

出版信息

Rev Med Chil. 1989 Sep;117(9):984-90.

PMID:2519481
Abstract

We show our experience, results and complications with Intermittent Peritoneal Dialysis (IPD). We treated with this technique 28 patients with end stage renal disease (ESRD), between 1981-1988; (24 adults, 8 of them with diabetic nephropathy (6 non insulin dependent diabetic patients and 4 children) for 3 to 36 months. IPD was well tolerated. The extracellular volume control, haematocrit and plasma protein values, as well as, ac-base equilibrium nutritional status, ureic nitrogen and creatinine plasma levels, were fully satisfactory. There was statistical difference only in the Na+ (p less than 0.001), alkaline phosphatases (p less than 0.005), glucose (p less than 0.05) plasma values and glycosylated hemoglobin (p less than 0.05), between diabetics and non diabetics group. The peritonitis rate was 0.065 and 0.074 peritonitis/patients-month; respectively (NS) and were caused by Gram (-) bacteria. St Aureus and St Epidermides. The survival curves of patients and method, in both groups, were similar (NS). We conclude IPD is a good alternative of therapy for ESRD, also for diabetics patients, whom haven't got more infection rate than non diabetics patients.

摘要

我们展示了间歇性腹膜透析(IPD)的经验、结果及并发症。1981年至1988年间,我们采用该技术治疗了28例终末期肾病(ESRD)患者;(24例成人,其中8例患有糖尿病肾病(6例非胰岛素依赖型糖尿病患者和4例儿童),治疗时间为3至36个月。IPD耐受性良好。细胞外液控制、血细胞比容和血浆蛋白值,以及酸碱平衡、营养状况、尿素氮和肌酐血浆水平均完全令人满意。糖尿病组和非糖尿病组之间仅在钠离子(p<0.001)、碱性磷酸酶(p<0.005)、葡萄糖(p<0.05)血浆值和糖化血红蛋白(p<0.05)方面存在统计学差异。腹膜炎发生率分别为0.065和0.074次腹膜炎/患者-月;(无显著性差异),由革兰氏阴性菌、金黄色葡萄球菌和表皮葡萄球菌引起。两组患者的生存曲线和治疗方法相似(无显著性差异)。我们得出结论,IPD是ESRD治疗的一种良好替代方法,对于糖尿病患者也是如此,其感染率并不高于非糖尿病患者。

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