Bjermer Leif
Department of Respiratory Medicine and Allergology, Skåne University Hospital, Lund, Sweden.
Respiration. 2014;88(4):346-52. doi: 10.1159/000363771. Epub 2014 Aug 29.
Inhaled therapies are central to the treatment of asthma and chronic obstructive pulmonary disease. Physicians consider many factors when selecting the most appropriate inhaler device, including device efficacy and the cost to the health care system. This review aims to discuss the factors that are important when considering inhaler devices and the importance of continuity in the choice of inhaler device. A large number of factors can contribute to therapeutic outcomes with inhalation devices. The inhalation technique is critical to treatment success and differs substantially between inhaler devices. Misuse of an inhaler is common, and thorough training of patients and physicians is important to ensure correct utilization. Patient satisfaction is an important consideration because it is significantly correlated with compliance and better outcomes. Financial pressures contribute to decision making: although selecting the less expensive inhaler device might reduce direct treatment costs, it can have a large impact on disease control and the patient's well-being. Switching may be associated with a poor inhalation technique, reduced disease control and quality of life, increased use of other treatments and health care resources, and a greater chance of unsuccessful treatment. Nonconsensual switches can result in patient discontent, reduced confidence in the medication, and uncertainty regarding the degree of disease control. It is recommended that patients with stable disease remain on their current device. If a switch is considered, the patient should be consulted and the physician should take into account the patient's preference, their ability to correctly use the device, and the availability of the preferred drug in the preferred device.
吸入疗法是哮喘和慢性阻塞性肺疾病治疗的核心。医生在选择最合适的吸入装置时会考虑许多因素,包括装置的疗效和对医疗保健系统的成本。本综述旨在讨论在考虑吸入装置时重要的因素以及吸入装置选择中连续性的重要性。大量因素会影响吸入装置的治疗效果。吸入技术对治疗成功至关重要,且不同吸入装置之间差异很大。吸入器使用不当很常见,对患者和医生进行全面培训对于确保正确使用很重要。患者满意度是一个重要的考虑因素,因为它与依从性和更好的治疗效果显著相关。经济压力会影响决策:虽然选择较便宜的吸入装置可能会降低直接治疗成本,但它可能对疾病控制和患者福祉产生重大影响。更换装置可能与吸入技术不佳、疾病控制和生活质量下降、其他治疗和医疗资源使用增加以及治疗失败的可能性增加有关。未经同意的更换可能导致患者不满、对药物的信心降低以及疾病控制程度的不确定性。建议病情稳定的患者继续使用当前装置。如果考虑更换,应咨询患者,医生应考虑患者的偏好、正确使用装置的能力以及首选装置中首选药物的可用性。