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使用腹腔镜方法进行食管旁疝修补术可改善患者预后:一项基于国家外科质量改进计划数据的研究

Improved patient outcomes in paraesophageal hernia repair using a laparoscopic approach: a study of the national surgical quality improvement program data.

作者信息

Kubasiak John, Hood Keith C, Daly Shaun, Deziel Daniel J, Myers Jonathan A, Millikan Keith W, Janssen Imke, Luu Minh B

机构信息

Department of General Surgery, Rush University Medical Center, Chicago, Illinois, USA.

出版信息

Am Surg. 2014 Sep;80(9):884-9.

PMID:25197875
Abstract

A consensus on the optimal surgical approach for repair of a paraesophageal hernia has not been reached. The aim of this study was to examine the outcomes of open and laparoscopic paraesophageal hernia repairs (PHR), both with and without mesh. A review of the National Surgical Quality Improvement Program (NSQIP) database from 2007 to 2011 was conducted. Patients who underwent an open or laparoscopic PHR were included. The primary outcome was 30-day mortality. Secondary outcomes included infections, respiratory and cardiac complications, intraoperative or perioperative transfusions, sepsis, and septic shock. Statistical analyses using odds ratios were performed comparing the open and laparoscopic approaches. A total of 4470 patients were identified using NSQIP; 2834 patients had a laparoscopic repair and the remaining 1636 patients underwent an open PHR. Compared with the laparoscopic approach, the open repair group had significantly higher 30-day mortality (odds ratio, 4.75; 95% confidence interval, 2.67 to 8.47; P < 0.0001). The laparoscopic approach had a statistically significant decrease in infections, respiratory and cardiac events/complications, transfusion requirements, episodes of sepsis, and septic shock (P < 0.05). Our data suggest increased perioperative morbidity associated with an open PHR compared with laparoscopic. There was no statistically significant difference in any of the primary or secondary outcomes in patients repaired with mesh compared with those without. The overall use of mesh in paraesophageal hernia repairs has increased. The NSQIP data show significantly increased 30-day mortality in open repair compared with laparoscopic as well as a significantly higher perioperative complication rate.

摘要

对于食管旁疝修补的最佳手术方法尚未达成共识。本研究的目的是探讨开放手术和腹腔镜下食管旁疝修补术(PHR)的疗效,包括使用补片和不使用补片的情况。我们对2007年至2011年国家外科质量改进计划(NSQIP)数据库进行了回顾。纳入接受开放手术或腹腔镜PHR的患者。主要结局是30天死亡率。次要结局包括感染、呼吸和心脏并发症、术中或围手术期输血、脓毒症和感染性休克。采用比值比进行统计分析,比较开放手术和腹腔镜手术方法。使用NSQIP共识别出4470例患者;2834例患者接受了腹腔镜修补术,其余1636例患者接受了开放PHR。与腹腔镜手术方法相比,开放修补组的30天死亡率显著更高(比值比,4.75;95%置信区间,2.67至8.47;P<0.0001)。腹腔镜手术方法在感染、呼吸和心脏事件/并发症、输血需求、脓毒症发作和感染性休克方面有统计学显著降低(P<0.05)。我们的数据表明,与腹腔镜手术相比,开放PHR的围手术期发病率更高。使用补片修补的患者与未使用补片的患者在任何主要或次要结局方面均无统计学显著差异。食管旁疝修补术中补片的总体使用有所增加。NSQIP数据显示,与腹腔镜手术相比,开放修补的30天死亡率显著增加,围手术期并发症发生率也显著更高。

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