Zhang Qiangqiang, Li Li, Yuli Kang, Zhao Ying, Zhu Junhao, Zhu Min
Department of Dermatology, Huashan Hospital, Fudan University, Shanghai, 200040, China,
Mycopathologia. 2015 Feb;179(1-2):163-6. doi: 10.1007/s11046-014-9812-y. Epub 2014 Sep 9.
We report a case of cutaneous protothecosis due to Prototheca wickerhamii in an immunocompetent man presented with a specific eczema-like lesions. Dermatological examination revealed erythematous plaques, dark red papules with some coalescence, and a few superficial ulcerations, covered with less scales on his right side chest and neck. Fungal culture, histopathological examination and molecular identification confirmed the organism. Antifungal susceptibility testing revealed strain sensitive to amphotericin B, Fluconazole, itraconazole and voriconazole. The patient was cured by oral itraconazole capsules and topical cream ketoconazole 2%.
我们报告一例由威克海默原藻引起的皮肤原藻病，患者为一名免疫功能正常的男性，表现为特异性湿疹样皮损。皮肤科检查发现右侧胸部和颈部有红斑性斑块、暗红色丘疹且部分融合，还有一些浅表溃疡，表面鳞屑较少。真菌培养、组织病理学检查及分子鉴定确诊了病原体。抗真菌药敏试验显示该菌株对两性霉素B、氟康唑、伊曲康唑和伏立康唑敏感。患者通过口服伊曲康唑胶囊和外用2%酮康唑乳膏治愈。
