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体外受精前不孕女性中遗传性和获得性血栓形成倾向的发生率研究。

Study of the frequency of occurrence of genetic and acquired thrombophilia in infertile women prior IVF.

作者信息

Petukhova N L, Tsaturova K A, Vartanian E V, Schigoleva A V, Markin A V

机构信息

ART Clinic "Test-tube babies" , Moscow , Russia.

出版信息

Gynecol Endocrinol. 2014 Oct;30 Suppl 1:32-4. doi: 10.3109/09513590.2014.945783.

DOI:10.3109/09513590.2014.945783
PMID:25200826
Abstract

This study of infertile women prior in vitro fertilization (IVF) is focused at the genetic and acquired thrombophilia before the IVF program, the identification of the frequency of occurrence of thrombophilia in them, the impact of thrombophilia of the offensive, the course and outcome of pregnancies, to improve the quality of cycles in terms of a pregnancy and childbirth. Forty-five women with infertility were examined. Thirty-two (71%) were identified thrombophilia: genetic thrombophilia in 32 cases (100%), among them a combination of several forms of genetic thrombophilia - 21 (63%) of them, other forms of thrombophilia (genetic and acquired) - in 5 of them (16%). In IVF 23 (72%) women became pregnant. In 87% of pregnancies ended in spontaneous birth, in 13% of cases of preterm birth.

摘要

这项针对体外受精(IVF)前不孕女性的研究聚焦于IVF程序前的遗传性和获得性血栓形成倾向,确定其血栓形成倾向的发生频率,血栓形成倾向对受孕、妊娠过程和结局的影响,以提高妊娠和分娩周期的质量。对45名不孕女性进行了检查。其中32名(71%)被确定存在血栓形成倾向:32例(100%)为遗传性血栓形成倾向,其中21例(63%)为几种遗传性血栓形成倾向的组合,另外5例(16%)为其他形式的血栓形成倾向(遗传性和获得性)。在IVF治疗中,23名(72%)女性怀孕。87%的妊娠以自然分娩结束,13%的病例为早产。

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