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IBD:粪便钙卫蛋白检测——需要更好的标准化。

IBD: Faecal calprotectin testing--the need for better standardization.

机构信息

Department of Gastroenterology, University Medical Clinic, Cantonal Hospital, CH-4410 Liestal, Switzerland.

Departments of Gastroenterology and Hepatology, University Hospital, Petersgraben 4, CH-4031 Basel, Switzerland.

出版信息

Nat Rev Gastroenterol Hepatol. 2014 Oct;11(10):583-4. doi: 10.1038/nrgastro.2014.154. Epub 2014 Sep 9.

Abstract

Measurement of faecal calprotectin concentration is increasingly used to assess disease activity in patients with IBD. Lasson et al. have now demonstrated that calprotectin concentrations in faeces of patients with mild or moderate left-sided or extensive ulcerative colitis vary considerably and have questioned the long-term stability of calprotectin when stored at room temperature.

摘要

粪便钙卫蛋白浓度的测定越来越多地用于评估 IBD 患者的疾病活动度。Lasson 等人现在已经证明,轻度或中度左侧或广泛性溃疡性结肠炎患者粪便中的钙卫蛋白浓度差异很大,并质疑在室温下储存时钙卫蛋白的长期稳定性。

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