Fukaya Ken, Tabata Toshiharu, Sugawara Takafumi, Yabuki Hiroshi, Murakami Kazuhiro, Fujimura Shigefumi
Department of Thoracic Surgery, Tohoku Pharmaceutical University Hospital, Japan.
Kyobu Geka. 2014 Sep;67(10):935-8.
We report a patient with primary malignant peripheral nerve sheath tumor (MPNST) of the lung. A 84-year-old man was referred to our hospital because of an abnormal shadow on chest X-ray. The computed tomography( CT) of the chest revealed a 6 cm tumor close to the posterior chest wall in the left thorax. He was followed-up because a benign tumor from posterior mediastinum was suspected. But the CT after 17 months showed the tumor enlargement. We performed complete resection under video-assisted thoracic surgery. It arose from the left lower lobe and was diagnosed as primary MPNST of the lung by immuno-histopathological examination. MPNSTs have a poor prognosis with tendency to recur. Although there is no sign of recurrence a year after surgery, we should follow-up carefully.
我们报告一例原发性肺恶性外周神经鞘瘤（MPNST）患者。一名84岁男性因胸部X光片出现异常阴影而转诊至我院。胸部计算机断层扫描（CT）显示左胸靠近后胸壁有一个6厘米的肿瘤。由于怀疑是后纵隔的良性肿瘤，对其进行了随访。但17个月后的CT显示肿瘤增大。我们在电视辅助胸腔镜手术下进行了完整切除。肿瘤起源于左下叶，经免疫组织病理学检查诊断为原发性肺MPNST。MPNST预后较差，有复发倾向。虽然术后一年没有复发迹象，但我们仍应仔细随访。
