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利用肌肉超声揭示老年人的肌肉减少症和衰弱——一篇叙述性综述。

Uncovering sarcopenia and frailty in older adults by using muscle ultrasound-A narrative review.

作者信息

Prell Tino, Grimm Alexander, Axer Hubertus

机构信息

Department of Geriatrics, Halle University Hospital, Halle, Germany.

Department of Neurology, Jena University Hospital, Jena, Germany.

出版信息

Front Med (Lausanne). 2024 May 17;11:1333205. doi: 10.3389/fmed.2024.1333205. eCollection 2024.

Abstract

Muscle ultrasound is a valuable non-invasive and cost-effective method in assessing muscle mass and structure, both of which are significant indicators for the development of sarcopenia and frailty in elderly individuals. Sarcopenia refers to the loss of muscle mass and strength that occurs with age, whereas frailty is a complex geriatric syndrome characterized by reduced physical function and an increased susceptibility to negative health outcomes. Both conditions are prevalent in older adults and are associated with higher risks of falls, disability, and mortality. By measuring muscle size and structure and several other ultrasound parameters, including muscle thickness, cross-sectional area, echogenicity (brightness in the ultrasound image), pennation angle, and fascicle length ultrasound can assist in identifying sarcopenia and frailty in older adults. In addition, ultrasound can be used to evaluate muscle function such as muscle contraction and stiffness, which may also be affected in sarcopenia and frailty. Therefore, muscle ultrasound could lead to better identification and tracking of sarcopenia and frailty. Such advancements could result in the implementation of earlier interventions to prevent or treat these conditions, resulting in an overall improvement in the health and quality of life of the elderly population. This narrative review describes the benefits and challenges when using ultra-sound for the evaluation of frailty and sarcopenia.

摘要

肌肉超声是评估肌肉质量和结构的一种有价值的非侵入性且经济高效的方法,而肌肉质量和结构都是老年人肌少症和衰弱症发展的重要指标。肌少症是指随着年龄增长而出现的肌肉质量和力量丧失,而衰弱是一种复杂的老年综合征,其特征是身体功能下降以及对不良健康结局的易感性增加。这两种情况在老年人中都很普遍,并且与跌倒、残疾和死亡的较高风险相关。通过测量肌肉大小和结构以及其他几个超声参数,包括肌肉厚度、横截面积、回声性(超声图像中的亮度)、羽状角和肌束长度,超声可以帮助识别老年人的肌少症和衰弱症。此外,超声可用于评估肌肉功能,如肌肉收缩和僵硬程度,而这些在肌少症和衰弱症中也可能受到影响。因此,肌肉超声可以更好地识别和跟踪肌少症和衰弱症。这些进展可能会促使实施早期干预措施来预防或治疗这些疾病,从而全面改善老年人群的健康和生活质量。这篇叙述性综述描述了使用超声评估衰弱症和肌少症时的益处和挑战。

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本文引用的文献

1
Human skeletal muscle-specific atrophy with aging: a comprehensive review.人类骨骼肌衰老性特异性萎缩:全面综述。
J Appl Physiol (1985). 2023 Apr 1;134(4):900-914. doi: 10.1152/japplphysiol.00768.2022. Epub 2023 Feb 24.
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Muscle Ultrasound as Imaging Domain of Frailty.肌肉超声作为衰弱的影像学领域。
Front Med (Lausanne). 2022 Jul 11;9:922345. doi: 10.3389/fmed.2022.922345. eCollection 2022.
7
The role of muscle ultrasound to predict sarcopenia.肌肉超声在预测肌肉减少症中的作用。
Nutrition. 2022 Sep;101:111692. doi: 10.1016/j.nut.2022.111692. Epub 2022 Apr 22.

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