Suppr超能文献

老年人在准备和执行复杂步行任务时对中枢神经系统资源的利用。

Utilization of central nervous system resources for preparation and performance of complex walking tasks in older adults.

机构信息

Brain Rehabilitation Research Center, Malcom Randall VA Medical Center, North Florida/South Georgia Veterans Health System Gainesville, FL, USA ; Department of Aging and Geriatric Research, University of Florida Gainesville, FL, USA.

Brain Rehabilitation Research Center, Malcom Randall VA Medical Center, North Florida/South Georgia Veterans Health System Gainesville, FL, USA ; Department of Physical Therapy, University of Florida Gainesville, FL, USA.

出版信息

Front Aging Neurosci. 2014 Aug 25;6:217. doi: 10.3389/fnagi.2014.00217. eCollection 2014.

Abstract

INTRODUCTION

Walking in the home and community often involves performance of complex walking tasks. Understanding the control of such tasks is crucial to preserving independence and quality of life in older adults. However, very little research has been conducted in this area. Here, we assess the extent to which two measures of central nervous system (CNS) activity are responsive to the challenges posed by preparation and performance of complex walking tasks. Prefrontal cortical activity was measured by functional near-infrared spectroscopy (fNIRS) and sympathetic nervous system arousal was measured by skin conductance level (SCL).

MATERIALS AND METHODS

Sixteen older men and women (age: 77.2 ± 5.6 years) with mild mobility deficits participated in this study. Participants walked at their preferred speed without distractions along an unobstructed, well-lit course (control task) and also walked on the same course under five separate challenging conditions: performing a cognitive verbal fluency task (verbal task), dim lighting (dim task), carrying a tray (carry task), negotiating obstacles (obstacles task) and wearing a weighted vest (vest task). Mean prefrontal activation and SCL were calculated during the preparation and performance phases of each task. Gait spatiotemporal measurements were acquired by an instrumented gait mat.

RESULTS

Prefrontal cortical activity and SCL were elevated during the preparation phase of complex walking tasks relative to the control task. During the performance phase, prefrontal activity remained elevated to a similar level as during task preparation. In contrast, SCL continued to increase beyond the level observed during task preparation. A larger increase in prefrontal activity was found to be linked to preserved quality of gait during complex walking tasks.

DISCUSSION

These findings indicate that availability and utilization of CNS resources are important for optimizing performance of complex walking tasks in older adults.

摘要

简介

在家中和社区中行走通常涉及执行复杂的行走任务。了解这些任务的控制对于保持老年人的独立性和生活质量至关重要。然而,在这一领域的研究非常少。在这里,我们评估了中枢神经系统(CNS)活动的两个测量指标在多大程度上对复杂行走任务的准备和执行所带来的挑战做出响应。前额叶皮质活动通过功能近红外光谱(fNIRS)进行测量,交感神经系统唤醒通过皮肤电导率水平(SCL)进行测量。

材料和方法

16 名年龄在 77.2 ± 5.6 岁、有轻度运动障碍的老年男性和女性参加了这项研究。参与者在没有干扰的情况下以自己喜欢的速度沿着无障碍、光线充足的路线行走(对照任务),并且在以下五个不同的挑战条件下沿着同一路线行走:执行认知口头流畅性任务(口头任务)、昏暗的灯光(昏暗任务)、携带托盘(携带任务)、障碍物(障碍任务)和穿负重背心(背心任务)。在每个任务的准备和执行阶段计算前额叶激活和 SCL 的平均值。通过仪器化步态垫采集步态时空测量值。

结果

与对照任务相比,在执行复杂行走任务的准备阶段,前额皮质活动和 SCL 升高。在执行阶段,前额叶活动仍然升高到与任务准备阶段相似的水平。相比之下,SCL 继续升高,超过了任务准备阶段观察到的水平。发现前额叶活动的增加幅度与在复杂行走任务中保持步态质量有关。

讨论

这些发现表明,中枢神经系统资源的可用性和利用对于优化老年人复杂行走任务的表现很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9770/4142860/c39facaa1c8f/fnagi-06-00217-g001.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验