Sun Zhiqi, Lambacher Armin, Fässler Reinhard
Max Planck Institute of Biochemistry, Department of Molecular Medicine, Am Klopferpsitz 18, 82152 Martinsried, Germany.
Max Planck Institute of Biochemistry, Department of Molecular Medicine, Am Klopferpsitz 18, 82152 Martinsried, Germany.
Curr Biol. 2014 Sep 8;24(17):R801-3. doi: 10.1016/j.cub.2014.07.061.
Integrins assemble a complex network of molecular interactions at cell-matrix adhesion sites. Fluorescence correlation microscopy has now shed light on the spatial, temporal and numerical distributions of protein complexes during assembly and stabilization of nascent adhesions.
整合素在细胞与基质的黏附位点组装了一个复杂的分子相互作用网络。荧光相关显微镜现已揭示了新生黏附组装和稳定过程中蛋白质复合物的空间、时间和数量分布情况。