果蝇小干扰RNA途径对病毒RNA的识别。

Viral RNA recognition by the Drosophila small interfering RNA pathway.

作者信息

Soares Zamira Guerra, Gonçalves André Nicolau Aquime, de Oliveira Karla Pollyanna Vieira, Marques João Trindade

机构信息

Department of Biochemistry and Immunology, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

出版信息

Microbes Infect. 2014 Dec;16(12):1013-21. doi: 10.1016/j.micinf.2014.09.001. Epub 2014 Sep 6.

DOI:10.1016/j.micinf.2014.09.001

PMID:25205243

Abstract

Viral RNA is a common activator of antiviral responses. In this review, we dissect the mechanism of viral RNA recognition by the small interfering RNA pathway in Drosophila melanogaster. This antiviral response in fruit flies can help understand general principles of nucleic acid recognition.

摘要

病毒RNA是抗病毒反应的常见激活剂。在本综述中，我们剖析了果蝇中小干扰RNA途径识别病毒RNA的机制。果蝇中的这种抗病毒反应有助于理解核酸识别的一般原理。