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唾液α淀粉酶作为牙科恐惧的非侵入性生物标志物及其与儿童牙科治疗期间行为的相关性。

Salivary Alpha Amylase as a Noninvasive Biomarker for Dental Fear and Its Correlation with Behavior of Children during Dental Treatment.

作者信息

Noorani Hina, Joshi Hrishikesh V, Shivaprakash Pk

机构信息

Professor and Head, Department of Pediatric and Preventive Dentistry, PM Nadagouda Memorial Dental College and Hospital, Bagalkot Karnataka, India.

Postgraduate Student, Department of Pediatric and Preventive Dentistry, PM Nadagouda Memorial Dental College and Hospital, Bagalkot Karnataka, India.

出版信息

Int J Clin Pediatr Dent. 2014 Jan;7(1):19-23. doi: 10.5005/jp-journals-10005-1227. Epub 2014 Apr 26.

DOI:10.5005/jp-journals-10005-1227
PMID:25206232
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4144055/
Abstract

OBJECTIVE

OBJECTIVEs of our studies were to predict dental fear in a child patient depending on salivary alpha amylase (sAA) level before and after dental treatment and to evaluate correla-tion of later with behavior of child patient during dental treatment.

MATERIALS AND METHODS

Seventy-seven children between age of 5 and 12 years were divided in three groups. Group 1 consisted of 25 school children who did not undergo any dental treatment. Groups 2 and 3 underwent dental treatment without and with local anesthesia respectively. Groups 2 and 3 were administered child fear survey schedule-dental subscale (CFSS-DS) questionnaire before treatment. Salivary samples were collected for sAA estimation in groups 2 and 3 children before and after completion of dental treatment and behavior during treatment was noted using Frankel behavior rating scale. Group 1 acted as control in which salivary sample was collected in absence of dental stress.

RESULTS

When groups 2 and 3 were combined, pretreatment sAA level had a statistically significant (p = 0.0094) correlation with CFSS-DS scores.

CONCLUSION

Alpha amylase can be used as a screening tool to predict level of dental fear in a child patient. How to cite this article: Noorani H, Joshi HV, Shivaprakash PK. Salivary Alpha Amylase as a Noninvasive Biomarker for Dental Fear and Its Correlation with Behavior of Children during Dental Treatment. Int J Clin Pediatr Dent 2014;7(1):19-23.

摘要

目的

我们研究的目的是根据儿童患者在牙科治疗前后唾液α淀粉酶(sAA)水平预测其牙科恐惧,并评估其与儿童患者在牙科治疗期间行为的相关性。

材料与方法

77名5至12岁的儿童被分为三组。第一组由25名未接受任何牙科治疗的学童组成。第二组和第三组分别在未使用局部麻醉和使用局部麻醉的情况下接受牙科治疗。第二组和第三组在治疗前接受儿童恐惧调查问卷-牙科分量表(CFSS-DS)问卷调查。在牙科治疗完成前后,收集第二组和第三组儿童的唾液样本以估计sAA,并使用弗兰克尔行为评定量表记录治疗期间的行为。第一组作为对照组,在没有牙科压力的情况下收集唾液样本。

结果

当将第二组和第三组合并时,治疗前sAA水平与CFSS-DS评分具有统计学显著相关性(p = 0.0094)。

结论

α淀粉酶可作为一种筛查工具来预测儿童患者的牙科恐惧程度。如何引用本文:Noorani H, Joshi HV, Shivaprakash PK. 唾液α淀粉酶作为牙科恐惧的非侵入性生物标志物及其与儿童牙科治疗期间行为的相关性。《国际临床儿科牙科学杂志》2014年;7(1):19 - 23。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/07a31530c73f/ijcpd-07-019-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/7ab513c581e9/ijcpd-07-019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/dc94dbcd1201/ijcpd-07-019-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/987e2096671b/ijcpd-07-019-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/07a31530c73f/ijcpd-07-019-i001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/7ab513c581e9/ijcpd-07-019-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/dc94dbcd1201/ijcpd-07-019-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/987e2096671b/ijcpd-07-019-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e1f2/4144055/07a31530c73f/ijcpd-07-019-i001.jpg

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