Tejnani Avneesh, Gandevivala Adil, Bhanushali Devang, Gourkhede Sonal
Department of Dental, Unit II, Consultant Periodontist, GSBS Medical Trust, Mumbai, Maharashtra, India.
Department of Oral and Maxillofacial Surgery, MGM Dental College, Navi Mumbai, Maharashtra, India.
J Indian Soc Periodontol. 2014 Jul;18(4):516-9. doi: 10.4103/0972-124X.138747.
Calcium channel blockers are widely used in medical practice for the management of hypertension and in the prophylaxis of angina. Gingival overgrowth is now a recognized unwanted effect associated with many of calcium channel blockers. This can have a significant effect on the quality of life as well as increasing the oral bacterial load by generating plaque retention sites. Amlodipine, a third generation calcium channel blockers has been shown to promote gingival overgrowth, although reported in very limited cases. The management of gingival overgrowth seems to be directed at controlling gingival inflammation through a good oral hygiene regimen. However, in severe cases, surgical excision is the most preferred method of treatment, followed by rigorous oral hygiene procedures. This case report describes the management of gingival overgrowth in a hypertensive patient taking amlodipine.
钙通道阻滞剂在医学实践中广泛用于治疗高血压和预防心绞痛。牙龈增生现在是许多钙通道阻滞剂公认的不良副作用。这会对生活质量产生重大影响，还会因产生牙菌斑滞留部位而增加口腔细菌载量。氨氯地平作为第三代钙通道阻滞剂，虽仅有非常有限的病例报道，但已显示会促使牙龈增生。牙龈增生的处理似乎是通过良好的口腔卫生措施来控制牙龈炎症。然而，在严重病例中，手术切除是最优选的治疗方法，随后要进行严格的口腔卫生程序。本病例报告描述了一名服用氨氯地平的高血压患者牙龈增生的处理情况。
