奈替米星引起的手足搐搦。
Netilmicin-induced carpopedal spasm.
作者信息
Ramani Roja Y, Panigrahy Benu, Rath Bandana
机构信息
Department of Pharmacology, Maharaja Krishna Chandra Gajapati Medical College and Hospital, Berhampur, Odisha, India.
Department of Urology, Maharaja Krishna Chandra Gajapati Medical College and Hospital, Berhampur, Odisha, India.
出版信息
J Pharmacol Pharmacother. 2014 Jul;5(3):211-3. doi: 10.4103/0976-500X.136112.
Aminoglycoside-induced nephrotoxicity is not uncommon. Netilmicin being a member of gentamicin family has the advantage of being relatively free from ototoxicity and nephrotoxicity and is also prescribed for gentamicin resistant cases. In spite of these benefits with netilmicin, occasional development of symptomatic hypomagnesemia, hypocalcemia, and hypokalemia due to renal electrolyte wasting cannot be ruled out. Here we describe two cases of carpopedal spasm due to hypocalcemia following use of netilmicin.
氨基糖苷类药物引起的肾毒性并不罕见。奈替米星作为庆大霉素家族的一员，具有相对无耳毒性和肾毒性的优势，也被用于治疗对庆大霉素耐药的病例。尽管奈替米星有这些益处，但由于肾脏电解质流失导致偶尔出现症状性低镁血症、低钙血症和低钾血症的情况仍不能排除。在此，我们描述两例使用奈替米星后因低钙血症导致手足痉挛的病例。
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