泪腺多形性腺瘤伴显著透明细胞肌上皮瘤成分
Pleomorphic Adenoma With Prominent Clear Cell Myoepithelioma Component of the Lacrimal Gland.
作者信息
Adekunle Adewumi N, Mendoza Pia R, Wojno Ted H, Grossniklaus Hans E
机构信息
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, U.S.A.
出版信息
Ophthalmic Plast Reconstr Surg. 2016 Jan-Feb;32(1):e18-21. doi: 10.1097/IOP.0000000000000374.
A case of a pleomorphic adenoma of the lacrimal gland with a prominent clear cell myoepitheliomatous component was reported. An 81-year-old Caucasian woman experienced a 2-month history of right supraorbital swelling and proptosis. Excisional biopsy revealed a multicomponent lesion including a stromal component featuring glandular structures made of small epithelioid and spindle cells and a trabecular component with small islands of vacuolated cells, displaced nuclei, and clear cytoplasm. Immunohistochemical analysis revealed strong cytokeratin AE1/3 reactivity and focal smooth muscle actin positivity. The pathologic findings including immunohistochemistry results were consistent with a pleomorphic adenoma with prominent clear cell myoepithelioma component.
报告了1例泪腺多形性腺瘤，伴有显著的透明细胞肌上皮瘤成分。一名81岁的白种女性有2个月的右上眶肿胀和眼球突出病史。切除活检显示为多成分病变，包括一个间质成分，其特征为有由小上皮样细胞和梭形细胞构成的腺管结构，以及一个小梁成分，有小的空泡化细胞岛、核移位和透明细胞质。免疫组化分析显示细胞角蛋白AE1/3呈强反应性，平滑肌肌动蛋白呈局灶性阳性。包括免疫组化结果在内的病理表现符合伴有显著透明细胞肌上皮瘤成分的多形性腺瘤。
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