Faria Eliane Rodrigues de, Faria Franciane Rocha de, Franceschini Sylvia do Carmo Castro, Peluzio Maria do Carmo Gouveia, Sant Ana Luciana Ferreira da Rocha, Novaes Juliana Farias de, Ribeiro Sônia Machado Rocha, Ribeiro Andréia Queiroz, Priore Silvia Eloiza
Departamento de Farmácia e Nutrição, Universidade Federal do Espírito Santo, Alegre, ES, Brasil.
Instituto de Ciências Biológicas e da Saúde, UFV, Rio Paranaíba, MG, Brasil.
Arq Bras Endocrinol Metabol. 2014 Aug;58(6):610-8. doi: 10.1590/0004-2730000002613.
To analyze the influence of metabolic syndrome components in insulin resistance, by gender and adolescence phase.
We evaluated biochemical, clinical, lifestyle and body composition data of 800 adolescents from 10 to 19 years old, from both genders, from Viçosa, MG/Brasil, and there was the division by stage: early (10 to 13 years), intermediate (14 to 16 years) and late (17 to 19 years).
10.3 and 3.4% had, respectively, insulin resistance and metabolic syndrome. In the initial phase there was a higher prevalence of dyslipidemia and intermediate hyperuricemia and excess body fat. Females had a higher prevalence of dyslipidemia, excess body fat and insulin resistance and higher male prevalence of low HDL, hyperuricemia and blood pressure changes. Those from the initial phase had higher levels of total cholesterol, LDL, HDL, triglycerides, fasting glucose and waist/hip ratio, stayed less time sitting and had more meals (p < 0.05) in relation to other phases. The final model, adjusted for gender, was different for each phase of adolescence.
Insulin resistance is associated with inadequate body composition, in biochemical levels and lifestyle, being the factors associated different in each phase of adolescence.
按性别和青春期阶段分析代谢综合征各组分对胰岛素抵抗的影响。
我们评估了来自巴西米纳斯吉拉斯州维索萨市的800名10至19岁青少年的生化、临床、生活方式和身体成分数据，这些青少年涵盖了两个性别，并按阶段进行了划分：早期（10至13岁）、中期（14至16岁）和晚期（17至19岁）。
分别有10.3%和3.4%的青少年存在胰岛素抵抗和代谢综合征。在初始阶段，血脂异常、中度高尿酸血症和体脂过多的患病率较高。女性血脂异常、体脂过多和胰岛素抵抗的患病率较高，而男性低高密度脂蛋白、高尿酸血症和血压变化的患病率较高。与其他阶段相比，处于初始阶段的青少年总胆固醇、低密度脂蛋白、高密度脂蛋白、甘油三酯、空腹血糖和腰臀比水平较高，久坐时间较短且进餐次数较多（p<0.05）。针对性别进行调整后的最终模型在青春期的每个阶段都有所不同。
胰岛素抵抗与身体成分、生化水平和生活方式不当有关，且在青春期的每个阶段相关因素都有所不同。
